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Cdc20: a potential novel therapeutic target for cancer treatment

The Anaphase Promoting Complex (APC) has been characterized to play pivotal roles in regulating the timely cell cycle progression by forming two functionally distinct E3 ubiquitin ligase sub-complexes, APC(Cdc20) and APC(Cdh1). Interestingly, recent studies have shown that Cdh1 is functioning as a t...

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Detalhes bibliográficos
Main Authors: Wang, Zhiwei, Wan, Lixin, Zhong, Jiateng, Inuzuka, Hiroyuki, Liu, Pengda, Sarkar, Fazlul H., Wei, Wenyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014638/
https://ncbi.nlm.nih.gov/pubmed/23151139
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