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Cdc20: a potential novel therapeutic target for cancer treatment

The Anaphase Promoting Complex (APC) has been characterized to play pivotal roles in regulating the timely cell cycle progression by forming two functionally distinct E3 ubiquitin ligase sub-complexes, APC(Cdc20) and APC(Cdh1). Interestingly, recent studies have shown that Cdh1 is functioning as a t...

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Autors principals: Wang, Zhiwei, Wan, Lixin, Zhong, Jiateng, Inuzuka, Hiroyuki, Liu, Pengda, Sarkar, Fazlul H., Wei, Wenyi
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014638/
https://ncbi.nlm.nih.gov/pubmed/23151139
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