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Cdc20: a potential novel therapeutic target for cancer treatment

The Anaphase Promoting Complex (APC) has been characterized to play pivotal roles in regulating the timely cell cycle progression by forming two functionally distinct E3 ubiquitin ligase sub-complexes, APC(Cdc20) and APC(Cdh1). Interestingly, recent studies have shown that Cdh1 is functioning as a t...

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Библиографические подробности
Главные авторы: Wang, Zhiwei, Wan, Lixin, Zhong, Jiateng, Inuzuka, Hiroyuki, Liu, Pengda, Sarkar, Fazlul H., Wei, Wenyi
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4014638/
https://ncbi.nlm.nih.gov/pubmed/23151139
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