A Clonal Expression Biomarker Associates With Lung Cancer Mortality

Molecular biomarkers aim to stratify cancer patients into disease subtypes predictive of outcome, improving diagnostic precision beyond clinical descriptors such as tumour stage(1). Transcriptomic intra-tumour heterogeneity (RNA-ITH) has been shown to confound existing expression-based biomarkers ac...

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I publikationen:Nat Med
Huvudupphovsmän: Biswas, Dhruva, Birkbak, Nicolai J, Rosenthal, Rachel, Hiley, Crispin T., Lim, Emilia L., Papp, Krisztian, Boeing, Stefan, Krzystanek, Marcin, Djureinovic, Dijana, La Fleur, Linnea, Greco, Maria, Döme, Balázs, Fillinger, János, Brunnström, Hans, Wu, Yin, Moore, David A., Skrzypski, Marcin, Abbosh, Christopher, Litchfield, Kevin, Al Bakir, Maise, Watkins, Thomas BK, Veeriah, Selvaraju, Wilson, Gareth A., Jamal-Hanjani, Mariam, Moldvay, Judit, Botling, Johan, Chinnaiyan, Arul M., Micke, Patrick, Hackshaw, Allan, Bartek, Jiri, Csabai, Istvan, Szallasi, Zoltan, Herrero, Javier, McGranahan, Nicholas, Swanton, Charles
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6984959/
https://ncbi.nlm.nih.gov/pubmed/31591602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41591-019-0595-z
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