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Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution
Immune evasion is a hallmark of cancer. Losing the ability to present neoantigens through human leukocyte antigen (HLA) loss may facilitate immune evasion. However, the polymorphic nature of the locus has precluded accurate HLA copy-number analysis. Here, we present loss of heterozygosity in human l...
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| Опубликовано в: : | Cell |
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| Главные авторы: | , , , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cell Press
2017
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5720478/ https://ncbi.nlm.nih.gov/pubmed/29107330 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.10.001 |
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