Computational optimisation of targeted DNA sequencing for cancer detection

Despite recent progress thanks to next-generation sequencing technologies, personalised cancer medicine is still hampered by intra-tumour heterogeneity and drug resistance. As most patients with advanced metastatic disease face poor survival, there is need to improve early diagnosis. Analysing circu...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Martinez, Pierre, McGranahan, Nicholas, Birkbak, Nicolai Juul, Gerlinger, Marco, Swanton, Charles
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6506443/
https://ncbi.nlm.nih.gov/pubmed/24296834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03309
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