Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL

Por Sulis, Maria Luisa, Saftig, Paul, Ferrando, Adolfo
Publicado em 2011

A conserved tetraspanin subfamily promotes Notch signaling in Caenorhabditis elegans and in human cells

Por Dunn, Cory D., Sulis, Maria Luisa, Ferrando, Adolfo A., Greenwald, Iva
Publicado em 2010

The SCF(FBW7) ubiquitin ligase complex as a tumor suppressor in T cell leukemia

Por Thompson, Benjamin J., Buonamici, Silvia, Sulis, Maria Luisa, Palomero, Teresa, Vilimas, Tomas, Basso, Giuseppe, Ferrando, Adolfo, Aifantis, Iannis
Publicado em 2007

NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL

Por Sulis, Maria Luisa, Williams, Odette, Palomero, Teresa, Tosello, Valeria, Pallikuppam, Sasikala, Real, Pedro J., Barnes, Kelly, Zuurbier, Linda, Meijerink, Jules P., Ferrando, Adolfo A.
Publicado em 2008

Activation of the PI3K Pathway in Cancer through Inhibition of PTEN by Exchange Factor P-REX2a

Por Fine, Barry, Hodakoski, Cindy, Koujak, Susan, Su, Tao, Saal, Lao H., Maurer, Matthew, Hopkins, Benjamin, Keniry, Megan, Sulis, Maria Luisa, Mense, Sarah, Hibshoosh, Hanina, Parsons, Ramon
Publicado em 2009

Disregulated expression of the transcription factor ThPOK during T-cell development leads to high incidence of T-cell lymphomas

Por Lee, Hyung-Ok, He, Xiao, Mookerjee-Basu, Jayati, Zhongping, Dai, Hua, Xiang, Nicolas, Emmanuelle, Sulis, Maria Luisa, Ferrando, Adolfo A., Testa, Joseph R., Kappes, Dietmar J.
Publicado no Proc Natl Acad Sci U S A (2015)

Gamma-secretase inhibitors reverse glucocorticoid resistance in T-ALL

Por Real, Pedro J., Tosello, Valeria, Palomero, Teresa, Castillo, Mireia, Hernando, Eva, de Stanchina, Elisa, Sulis, Maria Luisa, Barnes, Kelly, Sawai, Catherine, Homminga, Irene, Meijerink, Jules, Aifantis, Iannis, Basso, Giuseppe, Cordon-Cardo, Carlos, Ai, Walden, Ferrando, Adolfo
Publicado em 2008

NOTCH1 directly regulates c-MYC and activates a feed-forward-loop transcriptional network promoting leukemic cell growth

Por Palomero, Teresa, Lim, Wei Keat, Odom, Duncan T., Sulis, Maria Luisa, Real, Pedro J., Margolin, Adam, Barnes, Kelly C., O'Neil, Jennifer, Neuberg, Donna, Weng, Andrew P., Aster, Jon C., Sigaux, Francois, Soulier, Jean, Look, A. Thomas, Young, Richard A., Califano, Andrea, Ferrando, Adolfo A.
Publicado em 2006

A secreted PTEN phosphatase that enters cells to alter signaling and survival

Por Hopkins, Benjamin D., Fine, Barry, Steinbach, Nicole, Dendy, Meaghan, Rapp, Zachary, Shaw, Jacquelyn, Pappas, Kyrie, Yu, Jennifer S., Hodakoski, Cindy, Mense, Sarah, Klein, Joshua, Pegno, Sarah, Sulis, Maria-Luisa, Goldstein, Hannah, Amendolara, Benjamin, Lei, Liang, Maurer, Matthew, Bruce, Jeffrey, Canoll, Peter, Hibshoosh, Hanina, Parsons, Ramon
Publicado em 2013

Mutational loss of PTEN induces resistance to NOTCH1 inhibition in T-cell leukemia

Por Palomero, Teresa, Sulis, Maria Luisa, Cortina, Maria, Real, Pedro J., Barnes, Kelly, Ciofani, Maria, Caparros, Esther, Buteau, Jean, Brown, Kristy, Perkins, Sherrie L., Bhagat, Govind, Mishra, Archana, Basso, Giuseppe, Castillo, Mireia, Nagase, Satoru, Cordon-Cardo, Carlos, Parsons, Ramon, Zúñiga-Pflücker, Juan Carlos, Dominguez, Maria, Ferrando, Adolfo A.
Publicado em 2007

WT1 mutations in T-ALL

Por Tosello, Valeria, Mansour, Marc R., Barnes, Kelly, Paganin, Maddalena, Sulis, Maria Luisa, Jenkinson, Sarah, Allen, Christopher G., Gale, Rosemary E., Linch, David C., Palomero, Teresa, Real, Pedro, Murty, Vundavalli, Yao, Xiaopan, Richards, Susan M., Goldstone, Anthony, Rowe, Jacob, Basso, Giuseppe, Wiernik, Peter H., Paietta, Elisabeth, Pieters, Rob, Horstmann, Martin, Meijerink, Jules P. P., Ferrando, Adolfo A.
Publicado em 2009

Mutational landscape, clonal evolution patterns, and role of RAS mutations in relapsed acute lymphoblastic leukemia

Por Oshima, Koichi, Khiabanian, Hossein, da Silva-Almeida, Ana C., Tzoneva, Gannie, Abate, Francesco, Ambesi-Impiombato, Alberto, Sanchez-Martin, Marta, Carpenter, Zachary, Penson, Alex, Perez-Garcia, Arianne, Eckert, Cornelia, Nicolas, Concepción, Balbin, Milagros, Sulis, Maria Luisa, Kato, Motohiro, Koh, Katsuyoshi, Paganin, Maddalena, Basso, Giuseppe, Gastier-Foster, Julie M., Devidas, Meenakshi, Loh, Mignon L., Kirschner-Schwabe, Renate, Palomero, Teresa, Rabadan, Raul, Ferrando, Adolfo A.
Publicado no Proc Natl Acad Sci U S A (2016)

Implementation of next generation sequencing into pediatric hematology-oncology practice: moving beyond actionable alterations

Por Oberg, Jennifer A., Glade Bender, Julia L., Sulis, Maria Luisa, Pendrick, Danielle, Sireci, Anthony N., Hsiao, Susan J., Turk, Andrew T., Dela Cruz, Filemon S., Hibshoosh, Hanina, Remotti, Helen, Zylber, Rebecca J., Pang, Jiuhong, Diolaiti, Daniel, Koval, Carrie, Andrews, Stuart J., Garvin, James H., Yamashiro, Darrell J., Chung, Wendy K., Emerson, Stephen G., Nagy, Peter L., Mansukhani, Mahesh M., Kung, Andrew L.
Publicado no Genome Med (2016)

The TLX1 oncogene drives aneuploidy in T-cell transformation

Por De Keersmaecker, Kim, Real, Pedro Jose, Gatta, Giusy Della, Palomero, Teresa, Sulis, Maria Luisa, Tosello, Valeria, Van Vlierberghe, Pieter, Barnes, Kelly, Castillo, Mireia, Sole, Xavier, Hadler, Michael, Lenz, Jack, Aplan, Peter D., Kelliher, Michelle, Kee, Barbara L., Pandolfi, Pier Paolo, Kappes, Dietmar, Gounari, Fotini, Petrie, Howard, Van der Meulen, Joni, Speleman, Frank, Paietta, Elisabeth, Racevskis, Janis, Wiernik, Peter H., Rowe, Jacob M., Soulier, Jean, Avran, David, Cavé, Hélène, Dastugue, Nicole, Raimondi, Susana, Meijerink, Jules P.P., Cordon-Cardo, Carlos, Califano, Andrea, Ferrando, Adolfo A.
Publicado em 2010