Depression research: where are we now?

par Lee, Saebom, Jeong, Jaehoon, Kwak, Yongdo, Park, Sang Ki
Publié 2010

c-Abl and Parkinson’s Disease: Mechanisms and Therapeutic Potential

par Brahmachari, Saurav, Karuppagounder, Senthilkumar S., Ge, Preston, Lee, Saebom, Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Publié dans J Parkinsons Dis (2017)

Valproate Alters Dopamine Signaling in Association with Induction of Par-4 Protein Expression

par Lee, Saebom, Jeong, Jaehoon, Park, Young-Un, Kwak, Yongdo, Lee, Seol Ae, Lee, Haeryun, Son, Hyeon, Park, Sang Ki
Publié 2012

Correction: Valproate Alters Dopamine Signaling in Association with Induction of Par-4 Protein Expression

par Lee, Saebom, Jeong, Jaehoon, Park, Young-Un, Kwak, Yongdo, Lee, Seol Ae, Lee, Haeryun, Son, Hyeon, Park, Sang Ki
Publié 2014

Dopamine D1 Receptor (D1R) Expression Is Controlled by a Transcriptional Repressor Complex Containing DISC1

par Suh, Yeongjun, Noh, Su-Jin, Lee, Saebom, Suh, Bo Kyoung, Lee, Su Been, Choi, Jinhyuk, Jeong, Jaehoon, Kim, Sangjune, Park, Sang Ki
Publié dans Mol Neurobiol (2019)

Cdk5 Phosphorylates Dopamine D2 Receptor and Attenuates Downstream Signaling

par Jeong, Jaehoon, Park, Young-Un, Kim, Dae-Kyum, Lee, Saebom, Kwak, Yongdo, Lee, Seol-Ae, Lee, Haeryun, Suh, Yoo-Hun, Gho, Yong Song, Hwang, Daehee, Park, Sang Ki
Publié 2013

Cyclin-dependent Kinase 5 (Cdk5) Regulates the Function of CLOCK Protein by Direct Phosphorylation

par Kwak, Yongdo, Jeong, Jaehoon, Lee, Saebom, Park, Young-Un, Lee, Seol-Ae, Han, Dong-Hee, Kim, Joung-Hun, Ohshima, Toshio, Mikoshiba, Katsuhiko, Suh, Yoo-Hun, Cho, Sehyung, Park, Sang Ki
Publié 2013

α-Synuclein accumulation and GBA deficiency due to L444P GBA mutation contributes to MPTP-induced parkinsonism

par Yun, Seung Pil, Kim, Donghoon, Kim, Sangjune, Kim, SangMin, Karuppagounder, Senthilkumar S., Kwon, Seung-Hwan, Lee, Saebom, Kam, Tae-In, Lee, Suhyun, Ham, Sangwoo, Park, Jae Hong, Dawson, Valina L., Dawson, Ted M., Lee, Yunjong, Ko, Han Seok
Publié dans Mol Neurodegener (2018)

GBA1 deficiency negatively affects physiological α-synuclein tetramers and related multimers

par Kim, Sangjune, Yun, Seung Pil, Lee, Saebom, Umanah, George Essien, Bandaru, Veera Venkata Ratnam, Yin, Xiling, Rhee, Peter, Karuppagounder, Senthilkumar S., Kwon, Seung-Hwan, Lee, Hojae, Mao, Xiaobo, Kim, Donghoon, Pandey, Akhilesh, Lee, Gabsang, Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Publié dans Proc Natl Acad Sci U S A (2018)

The c-Abl inhibitor, Radotinib HCl, is neuroprotective in a preclinical Parkinson’s disease mouse model

par Lee, Saebom, Kim, Sangjune, Park, Yong Joo, Yun, Seung Pil, Kwon, Seung-Hwan, Kim, Donghoon, Kim, Dong Yeon, Shin, Jae Soo, Cho, Dae Jin, Lee, Gong Yeal, Ju, Hyun Soo, Yun, Hyo Jung, Park, Jae Hong, Kim, Wonjoong Richard, Jung, Eun Ah, Lee, Seulki, Ko, Han Seok
Publié dans Hum Mol Genet (2018)

Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s disease

par Kim, Sangjune, Kwon, Seung-Hwan, Kam, Tae-In, Panicker, Nikhil, Karuppagounder, Senthilkumar S., Lee, Saebom, Lee, Jun Hee, Kim, Wonjoong Richard, Kook, Minjee, Foss, Catherine A., Shen, Chentian, Lee, Hojae, Kulkarni, Subhash, Pasricha, Pankaj J., Lee, Gabsang, Pomper, Martin G., Dawson, Valina L., Dawson, Ted M., Ko, Han Seok
Publié dans Neuron (2019)

Parkin interacting substrate zinc finger protein 746 is a pathological mediator in Parkinson’s disease

par Brahmachari, Saurav, Lee, Saebom, Kim, Sangjune, Yuan, Changqing, Karuppagounder, Senthilkumar S, Ge, Preston, Shi, Rosa, Kim, Esther J, Liu, Alex, Kim, Donghoon, Quintin, Stephan, Jiang, Haisong, Kumar, Manoj, Yun, Seung Pil, Kam, Tae-In, Mao, Xiaobo, Lee, Yunjong, Swing, Deborah A, Tessarollo, Lino, Ko, Han Seok, Dawson, Valina L, Dawson, Ted M
Publié dans Brain (2019)

Blocking microglial activation of reactive astrocytes is neuroprotective in models of Alzheimer’s disease

par Park, Jong-Sung, Kam, Tae-In, Lee, Saebom, Park, Hyejin, Oh, Yumin, Kwon, Seung-Hwan, Song, Jae-Jin, Kim, Donghoon, Kim, Hyunhee, Jhaldiyal, Aanishaa, Na, Dong Hee, Lee, Kang Choon, Park, Eun Ji, Pomper, Martin G., Pletnikova, Olga, Troncoso, Juan C., Ko, Han Seok, Dawson, Valina L., Dawson, Ted M., Lee, Seulki
Publié dans Acta Neuropathol Commun (2021)

Graphene quantum dots prevent α-synucleinopathy in Parkinson’s disease

par Kim, Donghoon, Yoo, Je Min, Hwang, Heehong, Lee, Junghee, Lee, Su Hyun, Yun, Seung Pil, Park, Myung Jin, Lee, MinJun, Choi, Seulah, Kwon, Sang Ho, Lee, Saebom, Kwon, Seung-Hwan, Kim, Sangjune, Park, Yong Joo, Kinoshita, Misaki, Lee, Young-Ho, Shin, Seokmin, Paik, Seung R., Lee, Sung Joong, Lee, Seulki, Hong, Byung Hee, Ko, Han Seok
Publié dans Nat Nanotechnol (2018)

Block of A1 astrocyte conversion by microglia is neuroprotective in models of Parkinson’s disease

par Yun, Seung Pil, Kam, Tae-In, Panicker, Nikhil, Kim, SangMin, Oh, Yumin, Park, Jong-Sung, Kwon, Seung-Hwan, Park, Yong Joo, Karuppagounder, Senthilkumar S., Park, Hyejin, Kim, Sangjune, Oh, Nayeon, Kim, Nayoung Alice, Lee, Saebom, Brahmachari, Saurav, Mao, Xiaobo, Lee, Jun Hee, Kumar, Manoj, An, Daniel, Kang, Sung-Ung, Lee, Yunjong, Lee, Kang Choon, Na, Dong Hee, Kim, Donghoon, Lee, Sang Hun, Roschke, Viktor V., Liddelow, Shane A., Mari, Zoltan, Barres, Ben. A., Dawson, Valina L., Lee, Seulki, Dawson, Ted M., Ko, Han Seok
Publié dans Nat Med (2018)