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Genetic variants at CD28, PRDM1, and CD2/CD58 are associated with rheumatoid arthritis risk

To discover novel RA risk loci, we systematically examined 370 SNPs from 179 independent loci with p<0.001 in a published meta-analysis of RA GWAS of 3,393 cases and 12,462 controls(1). We used GRAIL(2), a computational method that applies statistical text mining to PubMed abstracts, to score the...

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Detalhes bibliográficos
Main Authors: Raychaudhuri, Soumya, Thomson, Brian P., Remmers, Elaine F., Eyre, Stephen, Hinks, Anne, Guiducci, Candace, Catanese, Joseph J., Xie, Gang, Stahl, Eli A., Chen, Robert, Alfredsson, Lars, Amos, Christopher I., Ardlie, Kristin G., Barton, Anne, Bowes, John, Burtt, Noel P., Chang, Monica, Coblyn, Jonathan, Costenbader, Karen H., Criswell, Lindsey A., Crusius, J. Bart A., Cui, Jing, De Jager, Phillip L., Ding, Bo, Emery, Paul, Flynn, Edward, Harrison, Pille, Hocking, Lynne J., Huizinga, Tom W. J., Kastner, Daniel L., Ke, Xiayi, Kurreeman, Fina A. S., Lee, Annette T., Liu, Xiangdong, Li, Yonghong, Martin, Paul, Morgan, Ann W., Padyukov, Leonid, Reid, David M., Seielstad, Mark, Seldin, Michael F., Shadick, Nancy A., Steer, Sophia, Tak, Paul P., Thomson, Wendy, van der Helm-van Mil, Annette H. M., van der Horst-Bruinsma, Irene E., Weinblatt, Michael E., Wilson, Anthony G., Wolbink, Gert Jan, Wordsworth, Paul, Altshuler, David, Karlson, Elizabeth W., Toes, Rene E. M., de Vries, Niek, Begovich, Ann B., Siminovitch, Katherine A., Worthington, Jane, Klareskog, Lars, Gregersen, Peter K., Daly, Mark J., Plenge, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142887/
https://ncbi.nlm.nih.gov/pubmed/19898481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.479
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