A Candidate Gene Approach Identifies the TRAF1/C5 Region as a Risk Factor for Rheumatoid Arthritis

BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disorder affecting ∼1% of the population. The disease results from the interplay between an individual's genetic background and unknown environmental triggers. Although human leukocyte antigens (HLAs) account for ∼30% of the heritabl...

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Detalhes bibliográficos
Main Authors: Kurreeman, Fina A. S, Padyukov, Leonid, Marques, Rute B, Schrodi, Steven J, Seddighzadeh, Maria, Stoeken-Rijsbergen, Gerrie, van der Helm-van Mil, Annette H. M, Allaart, Cornelia F, Verduyn, Willem, Houwing-Duistermaat, Jeanine, Alfredsson, Lars, Begovich, Ann B, Klareskog, Lars, Huizinga, Tom W. J, Toes, Rene E. M
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2007
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1976626/
https://ncbi.nlm.nih.gov/pubmed/17880261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.0040278
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