A role for the transcriptional repressor Blimp-1 in CD8 T cell exhaustion during chronic viral infection

Por Shin, Haina, Blackburn, Shawn D., Intlekofer, Andrew M., Kao, Charlly, Angelosanto, Jill M., Reiner, Steven L., Wherry, E. John
Publicado em 2009

Molecular and transcriptional basis of CD4(+) T cell dysfunction during chronic infection

Por Crawford, Alison, Angelosanto, Jill M., Kao, Charlly, Doering, Travis A., Odorizzi, Pamela M., Barnett, Burton E., Wherry, E. John
Publicado em 2014

Requirement for T-bet in the aberrant differentiation of unhelped memory CD8(+) T cells

Por Intlekofer, Andrew M., Takemoto, Naofumi, Kao, Charlly, Banerjee, Arnob, Schambach, Felix, Northrop, John K., Shen, Hao, Wherry, E. John, Reiner, Steven L.
Publicado em 2007

The Role of mGluR Copy Number Variation in Genetic and Environmental Forms of Syndromic Autism Spectrum Disorder

Por Wenger, Tara L., Kao, Charlly, McDonald-McGinn, Donna M., Zackai, Elaine H., Bailey, Alice, Schultz, Robert T., Morrow, Bernice E., Emanuel, Beverly S., Hakonarson, Hakon
Publicado no Sci Rep (2016)

LinkedSV for detection of mosaic structural variants from linked-read exome and genome sequencing data

Por Fang, Li, Kao, Charlly, Gonzalez, Michael V., Mafra, Fernanda A., Pellegrino da Silva, Renata, Li, Mingyao, Wenzel, Sören-Sebastian, Wimmer, Katharina, Hakonarson, Hakon, Wang, Kai
Publicado no Nat Commun (2019)

Learning-dependent chromatin remodeling highlights noncoding regulatory regions linked to autism

Por Koberstein, John N., Poplawski, Shane G., Wimmer, Mathieu E., Porcari, Giulia, Kao, Charlly, Gomes, Bruce, Risso, Davide, Hakonarson, Hakon, Zhang, Nancy R., Schultz, Robert T., Abel, Ted, Peixoto, Lucia
Publicado no Sci Signal (2018)

Copy number variation meta-analysis reveals a novel duplication at 9p24 associated with multiple neurodevelopmental disorders

Por Glessner, Joseph T., Li, Jin, Wang, Dai, March, Michael, Lima, Leandro, Desai, Akshatha, Hadley, Dexter, Kao, Charlly, Gur, Raquel E., Cohen, Nadine, Sleiman, Patrick M. A., Li, Qingqin, Hakonarson, Hakon
Publicado no Genome Med (2017)

The impact of the metabotropic glutamate receptor and other gene family interaction networks on autism

Por Hadley, Dexter, Wu, Zhi-liang, Kao, Charlly, Kini, Akshata, Mohamed-Hadley, Alisha, Thomas, Kelly, Vazquez, Lyam, Qiu, Haijun, Mentch, Frank, Pellegrino, Renata, Kim, Cecilia, Connolly, John, Glessner, Joseph, Hakonarson, Hakon
Publicado em 2014

T-bet represses expression of PD-1 and sustains virus-specific CD8 T cell responses during chronic infection

Por Kao, Charlly, Oestreich, Kenneth J., Paley, Michael A., Crawford, Alison, Angelosanto, Jill M., Ali, Mohammed-Alkhatim A., Intlekofer, Andrew M., Boss, Jeremy M., Reiner, Steven L., Weinmann, Amy S., Wherry, E. John
Publicado em 2011

Type I IFN response associated with mTOR activation in the TAFRO subtype of idiopathic multicentric Castleman disease

Por Pai, Ruth-Anne Langan, Japp, Alberto Sada, Gonzalez, Michael, Rasheed, Rozena F., Okumura, Mariko, Arenas, Daniel, Pierson, Sheila K., Powers, Victoria, Layman, Awo Akosua Kesewa, Kao, Charlly, Hakonarson, Hakon, van Rhee, Frits, Betts, Michael R., Kambayashi, Taku, Fajgenbaum, David C.
Publicado no JCI Insight (2020)

Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling

Por Elia, Josephine, Ungal, Grace, Kao, Charlly, Ambrosini, Alexander, De Jesus-Rosario, Nilsa, Larsen, Lene, Chiavacci, Rosetta, Wang, Tiancheng, Kurian, Christine, Titchen, Kanani, Sykes, Brian, Hwang, Sharon, Kumar, Bhumi, Potts, Jacqueline, Davis, Joshua, Malatack, Jeffrey, Slattery, Emma, Moorthy, Ganesh, Zuppa, Athena, Weller, Andrew, Byrne, Enda, Li, Yun R., Kraft, Walter K., Hakonarson, Hakon
Publicado no Nat Commun (2018)

Pathogenic variant in EPHB4 results in central conducting lymphatic anomaly

Por Li, Dong, Wenger, Tara L, Seiler, Christoph, March, Michael E, Gutierrez-Uzquiza, Alvaro, Kao, Charlly, Bhoj, Elizabeth, Tian, Lifeng, Rosenbach, Misha, Liu, Yichuan, Robinson, Nora, Behr, Mechenzie, Chiavacci, Rosetta, Hou, Cuiping, Wang, Tiancheng, Bakay, Marina, Pellegrino da Silva, Renata, Perkins, Jonathan A, Sleiman, Patrick, Levine, Michael A, Hicks, Patricia J, Itkin, Maxim, Dori, Yoav, Hakonarson, Hakon
Publicado no Hum Mol Genet (2018)

Rare copy number variants in over 100,000 European ancestry subjects reveal multiple disease associations

Por Li, Yun Rose, Glessner, Joseph T., Coe, Bradley P., Li, Jin, Mohebnasab, Maede, Chang, Xiao, Connolly, John, Kao, Charlly, Wei, Zhi, Bradfield, Jonathan, Kim, Cecilia, Hou, Cuiping, Khan, Munir, Mentch, Frank, Qiu, Haijun, Bakay, Marina, Cardinale, Christopher, Lemma, Maria, Abrams, Debra, Bridglall-Jhingoor, Andrew, Behr, Meckenzie, Harrison, Shanell, Otieno, George, Thomas, Alexandria, Wang, Fengxiang, Chiavacci, Rosetta, Wu, Lawrence, Hadley, Dexter, Goldmuntz, Elizabeth, Elia, Josephine, Maris, John, Grundmeier, Robert, Devoto, Marcella, Keating, Brendan, March, Michael, Pellagrino, Renata, Grant, Struan F. A., Sleiman, Patrick M. A., Li, Mingyao, Eichler, Evan E., Hakonarson, Hakon
Publicado no Nat Commun (2020)

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases

Por Li, Yun R, Li, Jin, Zhao, Sihai D, Bradfield, Jonathan P, Mentch, Frank D, Maggadottir, S Melkorka, Hou, Cuiping, Abrams, Debra J, Chang, Diana, Gao, Feng, Guo, Yiran, Wei, Zhi, Connolly, John J, Cardinale, Christopher J, Bakay, Marina, Glessner, Joseph T, Li, Dong, Kao, Charlly, Thomas, Kelly A, Qiu, Haijun, Chiavacci, Rosetta M, Kim, Cecilia E, Wang, Fengxiang, Snyder, James, Richie, Marylyn D, Flatø, Berit, Førre, Øystein, Denson, Lee A, Thompson, Susan D, Becker, Mara L, Guthery, Stephen L, Latiano, Anna, Perez, Elena, Resnick, Elena, Russell, Richard K, Wilson, David C, Silverberg, Mark S, Annese, Vito, Lie, Benedicte A, Punaro, Marilynn, Dubinsky, Marla C, Monos, Dimitri S, Strisciuglio, Caterina, Staiano, Annamaria, Miele, Erasmo, Kugathasan, Subra, Ellis, Justine A, Munro, Jane E, Sullivan, Kathleen E, Wise, Carol A, Chapel, Helen, Cunningham-Rundles, Charlotte, Grant, Struan F A, Orange, Jordan S, Sleiman, Patrick M A, Behrens, Edward M, Griffiths, Anne M, Satsangi, Jack, Finkel, Terri H, Keinan, Alon, Prak, Eline T Luning, Polychronakos, Constantin, Baldassano, Robert N, Li, Hongzhe, Keating, Brendan J, Hakonarson, Hakon
Publicado no Nat Med (2015)

The copy number variation landscape of congenital anomalies of the kidney and urinary tract

Por Verbitsky, Miguel, Westland, Rik, Perez, Alejandra, Kiryluk, Krzysztof, Liu, Qingxue, Krithivasan, Priya, Mitrotti, Adele, Fasel, David A., Batourina, Ekaterina, Sampson, Matthew G., Bodria, Monica, Werth, Max, Kao, Charlly, Martino, Jeremiah, Capone, Valentina P., Vivante, Asaf, Shril, Shirlee, Kil, Byum Hee, Marasa, Maddalena, Zhang, Jun Y., Na, Young-Ji, Lim, Tze Y., Ahram, Dina, Weng, Patricia L., Heinzen, Erin L., Carrea, Alba, Piaggio, Giorgio, Gesualdo, Loreto, Manca, Valeria, Masnata, Giuseppe, Gigante, Maddalena, Cusi, Daniele, Izzi, Claudia, Scolari, Francesco, van Wijk, Joanna A.E., Saraga, Marijan, Santoro, Domenico, Conti, Giovanni, Zamboli, Pasquale, White, Hope, Drozdz, Dorota, Zachwieja, Katarzyna, Miklaszewska, Monika, Tkaczyk, Marcin, Tomczyk, Daria, Krakowska, Anna, Sikora, Przemyslaw, Jarmoliński, Tomasz, Borszewska-Kornacka, Maria K., Pawluch, Robert, Szczepanska, Maria, Adamczyk, Piotr, Mizerska-Wasiak, Malgorzata, Krzemien, Grazyna, Szmigielska, Agnieszka, Zaniew, Marcin, Dobson, Mark G., Darlow, John M., Puri, Prem, Barton, David E., Furth, Susan L., Warady, Bradley A., Gucev, Zoran, Lozanovski, Vladimir J., Tasic, Velibor, Pisani, Isabella, Allegri, Landino, Rodas, Lida M., Campistol, Josep M., Jeanpierre, Cécile, Alam, Shumyle, Casale, Pasquale, Wong, Craig S., Lin, Fangming, Miranda, Débora M., Oliveira, Eduardo A., Simões-e-Silva, Ana Cristina, Barasch, Jonathan M., Levy, Brynn, Wu, Nan, Hildebrandt, Friedhelm, Ghiggeri, Gian Marco, Latos-Bielenska, Anna, Materna-Kiryluk, Anna, Zhang, Feng, Hakonarson, Hakon, Papaioannou, Virginia E., Mendelsohn, Cathy L., Gharavi, Ali G., Sanna-Cherchi, Simone
Publicado no Nat Genet (2018)