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Molecular and transcriptional basis of CD4(+) T cell dysfunction during chronic infection
T cell exhaustion is common during chronic infections. While CD4(+) T cells are critical for controlling viral load during chronic viral infections, less is known about their differentiation and transcriptional program. We defined the phenotypic, functional and molecular profiles of exhausted CD4(+)...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3990591/ https://ncbi.nlm.nih.gov/pubmed/24530057 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2014.01.005 |
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