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Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8(+) T Cell Exhaustion versus Memory

Exhausted CD8(+) T cells function poorly and are negatively regulated by inhibitory receptors. Transcriptional profiling has identified gene expression changes associated with exhaustion. However, the transcriptional pathways critical to the differences between exhausted and functional memory CD8(+)...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Doering, Travis A., Crawford, Alison, Angelosanto, Jill M., Paley, Michael A., Ziegler, Carly G., Wherry, E. John
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3749234/
https://ncbi.nlm.nih.gov/pubmed/23159438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.08.021
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