Genetic absence of PD-1 promotes accumulation of terminally differentiated exhausted CD8(+) T cells

Por Odorizzi, Pamela M., Pauken, Kristen E., Paley, Michael A., Sharpe, Arlene, Wherry, E. John
Publicado no J Exp Med (2015)

Network Analysis Reveals Centrally Connected Genes and Pathways Involved in CD8(+) T Cell Exhaustion versus Memory

Por Doering, Travis A., Crawford, Alison, Angelosanto, Jill M., Paley, Michael A., Ziegler, Carly G., Wherry, E. John
Publicado em 2012

Technical Advance: Fluorescent reporter reveals insights into eomesodermin biology in cytotoxic lymphocytes

Por Paley, Michael A., Gordon, Scott M., Bikoff, Elizabeth K., Robertson, Elizabeth J., Wherry, E. John, Reiner, Steven L.
Publicado em 2013

Inhibition of Neutrophil Function by Two Tick Salivary Proteins

Por Guo, Xiuyang, Booth, Carmen J., Paley, Michael A., Wang, Xiaomei, DePonte, Kathleen, Fikrig, Erol, Narasimhan, Sukanya, Montgomery, Ruth R.
Publicado em 2009

The Transcription Factor Eomesodermin Enables CD8(+) T Cells to Compete for the Memory Cell Niche

Por Banerjee, Arnob, Gordon, Scott M., Intlekofer, Andrew M., Paley, Michael A., Mooney, Erin C., Lindsten, Tulia, Wherry, E. John, Reiner, Steven L.
Publicado em 2010

Bioenergetic insufficiencies due to metabolic alterations regulated by PD-1 are an early driver of CD8(+) T cell exhaustion

Por Bengsch, Bertram, Johnson, Andy L., Kurachi, Makoto, Odorizzi, Pamela M, Pauken, Kristen E., Attanasio, John, Stelekati, Erietta, McLane, Laura M., Paley, Michael A., Delgoffe, Greg M., Wherry, E. John
Publicado no Immunity (2016)

T-bet represses expression of PD-1 and sustains virus-specific CD8 T cell responses during chronic infection

Por Kao, Charlly, Oestreich, Kenneth J., Paley, Michael A., Crawford, Alison, Angelosanto, Jill M., Ali, Mohammed-Alkhatim A., Intlekofer, Andrew M., Boss, Jeremy M., Reiner, Steven L., Weinmann, Amy S., Wherry, E. John
Publicado em 2011

Commensal Bacteria Calibrate the Activation Threshold of Innate Antiviral Immunity

Por Abt, Michael C., Osborne, Lisa C., Monticelli, Laurel A., Doering, Travis A., Alenghat, Theresa, Sonnenberg, Gregory F., Paley, Michael A., Antenus, Marcelo, Williams, Katie L., Erikson, Jan, Wherry, E. John, Artis, David
Publicado em 2012

Progenitor and Terminal Subsets of CD8(+) T Cells Cooperate to Contain Chronic Viral Infection

Por Paley, Michael A., Kroy, Daniela C., Odorizzi, Pamela M., Johnnidis, Jonathan B., Dolfi, Douglas V., Barnett, Burton E., Bikoff, Elizabeth K., Robertson, Elizabeth J., Lauer, Georg M., Reiner, Steven L., Wherry, E. John
Publicado em 2012

B cell intrinsic T-bet expression is required to control chronic viral infection

Por Barnett, Burton E., Staupe, Ryan P., Odorizzi, Pamela M., Palko, Olesya, Tomov, Vesselin T., Mahan, Alison E., Gunn, Bronwyn, Chen, Diana, Paley, Michael A., Alter, Galit, Reiner, Steven L., Lauer, Georg M., Teijaro, John, Wherry, E. John
Publicado no J Immunol (2016)