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The Transcription Factor Eomesodermin Enables CD8(+) T Cells to Compete for the Memory Cell Niche

CD8(+) T cells responding to intracellular infection give rise to cellular progeny that become terminally differentiated effector cells and self-renewing memory cells. T-bet and Eomesodermin are key transcription factors of cytotoxic lymphocyte lineages. We now show that CD8(+) T cells lacking Eomes...

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Hlavní autoři: Banerjee, Arnob, Gordon, Scott M., Intlekofer, Andrew M., Paley, Michael A., Mooney, Erin C., Lindsten, Tulia, Wherry, E. John, Reiner, Steven L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975552/
https://ncbi.nlm.nih.gov/pubmed/20935204
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002042
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