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Eomesodermin driven IL-10 production in effector CD8(+) T cells promotes a memory phenotype.

CD8(+) T cell differentiation is controlled by the transcription factors T-bet and Eomesodermin, in concert with the cytokines IL-2, IL-10 and IL-12. Among these pathways, the mechanisms by which T-box proteins and IL-10 interact to promote a memory T cell fate remain poorly understood. Here, we sho...

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Detalhes bibliográficos
Publicado no:Cell Immunol
Main Authors: Reiser, John, Sadashivaiah, Kavitha, Furusawa, Aki, Banerjee, Arnob, Singh, Nevil
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6449173/
https://ncbi.nlm.nih.gov/pubmed/30528350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2018.11.008
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