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Eomesodermin driven IL-10 production in effector CD8(+) T cells promotes a memory phenotype.
CD8(+) T cell differentiation is controlled by the transcription factors T-bet and Eomesodermin, in concert with the cytokines IL-2, IL-10 and IL-12. Among these pathways, the mechanisms by which T-box proteins and IL-10 interact to promote a memory T cell fate remain poorly understood. Here, we sho...
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| Publié dans: | Cell Immunol |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6449173/ https://ncbi.nlm.nih.gov/pubmed/30528350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2018.11.008 |
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