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Eomesodermin increases survival and IL-2 responsiveness of tumor-specific CD8(+) T cells in an adoptive transfer model of cancer immunotherapy
Tumor-specific CD8(+) T cells often fail to elicit effective antitumor immune responses due to an inability to expand into a substantial effector population and persist long-term in vivo. Using an adoptive transfer model of cancer immunotherapy, we demonstrate that constitutive Eomes expression in t...
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| Publicado no: | J Immunother |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5801069/ https://ncbi.nlm.nih.gov/pubmed/29271784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000206 |
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