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Eomesodermin is required for antitumor immunity mediated by 4-1BB-agonist immunotherapy

CD8(+) T cells in progressing tumors frequently fail to mount an effective antitumor response often in association with the expression of inhibitory receptors, including programmed cell death-1 (PD-1) and lymphocyte-activation gene 3 (Lag3). Using a lymphoma tumor model, we demonstrate that tumor-in...

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Hlavní autoři: Song, Chang, Sadashivaiah, Kavitha, Furusawa, Aki, Davila, Eduardo, Tamada, Koji, Banerjee, Arnob
Médium: Artigo
Jazyk:Inglês
Vydáno: Landes Bioscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4002624/
https://ncbi.nlm.nih.gov/pubmed/24790793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.27680
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