STAT5 inhibition induces TRAIL/DR4 dependent apoptosis in peripheral T-cell lymphoma

Peripheral T-cell lymphoma (PTCL) is a rare, aggressive, heterogeneous, Non-Hodgkin's lymphoma with poor prognosis and inadequate response to current therapies. Recent sequencing studies indicate a prevalence of activating mutations in the JAK/STAT signaling pathway. Oncogenic mutations in STAT...

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Udgivet i:Oncotarget
Main Authors: Simpson, Haley M., Furusawa, Aki, Sadashivaiah, Kavitha, Civin, Curt I., Banerjee, Arnob
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2018
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908286/
https://ncbi.nlm.nih.gov/pubmed/29682185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24698
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