STAT5 inhibition induces TRAIL/DR4 dependent apoptosis in peripheral T-cell lymphoma

Peripheral T-cell lymphoma (PTCL) is a rare, aggressive, heterogeneous, Non-Hodgkin's lymphoma with poor prognosis and inadequate response to current therapies. Recent sequencing studies indicate a prevalence of activating mutations in the JAK/STAT signaling pathway. Oncogenic mutations in STAT...

Full description

Saved in:
Bibliographic Details
Published in:Oncotarget
Main Authors: Simpson, Haley M., Furusawa, Aki, Sadashivaiah, Kavitha, Civin, Curt I., Banerjee, Arnob
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2018
Subjects:
Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5908286/
https://ncbi.nlm.nih.gov/pubmed/29682185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.24698
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items