A role for the transcriptional repressor Blimp-1 in CD8 T cell exhaustion during chronic viral infection

T cell exhaustion is common during chronic infections and can prevent optimal immunity. While recent studies have demonstrated the importance of inhibitory receptors and other pathways in T cell exhaustion, the underlying transcriptional mechanisms are unknown. Here, we define a role for the transcr...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Shin, Haina, Blackburn, Shawn D., Intlekofer, Andrew M., Kao, Charlly, Angelosanto, Jill M., Reiner, Steven L., Wherry, E. John
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2747257/
https://ncbi.nlm.nih.gov/pubmed/19664943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.06.019
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker