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A role for the transcriptional repressor Blimp-1 in CD8 T cell exhaustion during chronic viral infection
T cell exhaustion is common during chronic infections and can prevent optimal immunity. While recent studies have demonstrated the importance of inhibitory receptors and other pathways in T cell exhaustion, the underlying transcriptional mechanisms are unknown. Here, we define a role for the transcr...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2747257/ https://ncbi.nlm.nih.gov/pubmed/19664943 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2009.06.019 |
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