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Type I IFN response associated with mTOR activation in the TAFRO subtype of idiopathic multicentric Castleman disease

The TAFRO clinical subtype of idiopathic multicentric Castleman disease (iMCD-TAFRO) is a rare hematologic illness involving episodic disease flares of thrombocytopenia, anasarca, fever, reticulin myelofibrosis, renal dysfunction, and organomegaly (TAFRO) and progressive multiple organ dysfunction....

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Pai, Ruth-Anne Langan, Japp, Alberto Sada, Gonzalez, Michael, Rasheed, Rozena F., Okumura, Mariko, Arenas, Daniel, Pierson, Sheila K., Powers, Victoria, Layman, Awo Akosua Kesewa, Kao, Charlly, Hakonarson, Hakon, van Rhee, Frits, Betts, Michael R., Kambayashi, Taku, Fajgenbaum, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253017/
https://ncbi.nlm.nih.gov/pubmed/32376796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135031
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