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Type I IFN response associated with mTOR activation in the TAFRO subtype of idiopathic multicentric Castleman disease

The TAFRO clinical subtype of idiopathic multicentric Castleman disease (iMCD-TAFRO) is a rare hematologic illness involving episodic disease flares of thrombocytopenia, anasarca, fever, reticulin myelofibrosis, renal dysfunction, and organomegaly (TAFRO) and progressive multiple organ dysfunction....

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Bibliografiska uppgifter
I publikationen:JCI Insight
Huvudupphovsmän: Pai, Ruth-Anne Langan, Japp, Alberto Sada, Gonzalez, Michael, Rasheed, Rozena F., Okumura, Mariko, Arenas, Daniel, Pierson, Sheila K., Powers, Victoria, Layman, Awo Akosua Kesewa, Kao, Charlly, Hakonarson, Hakon, van Rhee, Frits, Betts, Michael R., Kambayashi, Taku, Fajgenbaum, David C.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253017/
https://ncbi.nlm.nih.gov/pubmed/32376796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135031
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