Type I IFN response associated with mTOR activation in the TAFRO subtype of idiopathic multicentric Castleman disease

The TAFRO clinical subtype of idiopathic multicentric Castleman disease (iMCD-TAFRO) is a rare hematologic illness involving episodic disease flares of thrombocytopenia, anasarca, fever, reticulin myelofibrosis, renal dysfunction, and organomegaly (TAFRO) and progressive multiple organ dysfunction....

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Veröffentlicht in:JCI Insight
Hauptverfasser: Pai, Ruth-Anne Langan, Japp, Alberto Sada, Gonzalez, Michael, Rasheed, Rozena F., Okumura, Mariko, Arenas, Daniel, Pierson, Sheila K., Powers, Victoria, Layman, Awo Akosua Kesewa, Kao, Charlly, Hakonarson, Hakon, van Rhee, Frits, Betts, Michael R., Kambayashi, Taku, Fajgenbaum, David C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7253017/
https://ncbi.nlm.nih.gov/pubmed/32376796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135031
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