Increased mTOR activation in idiopathic multicentric Castleman disease

Idiopathic multicentric Castleman disease (iMCD) is a rare and poorly understood hematologic disorder characterized by lymphadenopathy, systemic inflammation, cytopenias, and life-threatening multiorgan dysfunction. Interleukin-6 (IL-6) inhibition effectively treats approximately one-third of patien...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Arenas, Daniel J., Floess, Katherine, Kobrin, Dale, Pai, Ruth-Anne Langan, Srkalovic, Maya B., Tamakloe, Mark-Avery, Rasheed, Rozena, Ziglar, Jasira, Khor, Johnson, Parente, Sophia A. T., Pierson, Sheila K., Martinez, Daniel, Wertheim, Gerald B., Kambayashi, Taku, Baur, Joseph, Teachey, David T., Fajgenbaum, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2020
Assuntos:
Lymphoid Neoplasia
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7205815/
https://ncbi.nlm.nih.gov/pubmed/32206779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood.2019002792
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