Unfolding tyrosine kinase inhibitor sensitivity in chronic myeloid leukemia

Por Perrotti, Danilo, Neviani, Paolo
Publicado em 2012

Targeting A Tumor Suppressor To Suppress Tumor Growth: News and Views on Protein Phosphatase 2A (PP2A) as a Target for Anti-cancer Therapy

Por Perrotti, Danilo, Neviani, Paolo
Publicado em 2013

SETting OP449 into the PP2A-Activating-Drug family

Por Neviani, Paolo, Perrotti, Danilo
Publicado no Clin Cancer Res (2014)

A “RANning” leap with “XPOrt” into TKI resistance

Por Rassool, Feyruz, Perrotti, Danilo
Publicado no Blood (2015)

BCR–ABL1 kinase-dependent alteration of mRNA metabolism: potential alternatives for therapeutic intervention

Por PERROTTI, DANILO, HARB, JASON G.
Publicado no Leuk Lymphoma (2011)

The new role of microRNAs in cancer

Por Perrotti, Danilo, Eiring, Anna M
Publicado no Future Oncol (2010)

From the Biology of PP2A to the PADs for Therapy of Hematologic Malignancies

Por Ciccone, Maria, Calin, George A., Perrotti, Danilo
Publicado no Front Oncol (2015)

Chronic myeloid leukemia: mechanisms of blastic transformation

Por Perrotti, Danilo, Jamieson, Catriona, Goldman, John, Skorski, Tomasz
Publicado em 2010

Resistance to apoptosis in CTLL-2 cells constitutively expressing c-Myb is associated with induction of BCL-2 expression and Myb-dependent regulation of bcl-2 promoter activity

Por Salomoni, Paolo, Perrotti, Danilo, Martinez, Robert, Franceschi, Claudio, Calabretta, Bruno
Publicado em 1997

Cellular and Molecular Networks in Chronic Myeloid Leukemia: The Leukemic Stem, Progenitor and Stromal Cell Interplay

Por Perrotti, Danilo, Silvestri, Giovannino, Stramucci, Lorenzo, Yu, Justine, Trotta, Rossana
Publicado no Curr Drug Targets (2017)

Antileukemia effect of c-myc N3′→P5′ phosphoramidate antisense oligonucleotides in vivo

Por Skorski, Tomasz, Perrotti, Danilo, Nieborowska-Skorska, Malgorzata, Gryaznov, Sergei, Calabretta, Bruno
Publicado em 1997

Chronic myeloid leukemia: the basis of treatment for tomorrow

Por Carella, Angelo M., Goldman, John M., Martinelli, Giovanni, Melo, Junia V., Perrotti, Danilo
Publicado em 2011

Blastic transformation of p53-deficient bone marrow cells by p210(bcr/abl) tyrosine kinase

Por Skorski, Tomasz, Nieborowska-Skorska, Malgorzata, Wlodarski, Pawel, Perrotti, Danilo, Martinez, Robert, Wasik, Mariusz A., Calabretta, Bruno
Publicado em 1996

Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis

Por Iozzo, Renato V., Chakrani, Fatima, Perrotti, Danilo, McQuillan, David J., Skorski, Tomasz, Calabretta, Bruno, Eichstetter, Inge
Publicado em 1999

CCAAT/enhancer binding proteins alpha and epsilon cooperate with all-trans retinoic acid in therapy but differ in their antileukemic activities

Por Lee, Young-Jin, Jones, Letetia C., Timchenko, Nikolai A., Perrotti, Danilo, Tenen, Daniel G., Kogan, Scott C.
Publicado em 2006

BCR-ABL Prevents c-Jun-Mediated and Proteasome-Dependent FUS (TLS) Proteolysis through a Protein Kinase CβII-Dependent Pathway

Por Perrotti, Danilo, Iervolino, Angela, Cesi, Vincenzo, Cirinná, Maria, Lombardini, Silvia, Grassilli, Emanuela, Bonatti, Silvia, Claudio, Pier Paolo, Calabretta, Bruno
Publicado em 2000

hnRNP A1 Nucleocytoplasmic Shuttling Activity Is Required for Normal Myelopoiesis and BCR/ABL Leukemogenesis

Por Iervolino, Angela, Santilli, Giorgia, Trotta, Rossana, Guerzoni, Clara, Cesi, Vincenzo, Bergamaschi, Anna, Gambacorti-Passerini, Carlo, Calabretta, Bruno, Perrotti, Danilo
Publicado em 2002

c-MYC Generates Repair Errors via Increased Transcription of Alternative-NHEJ Factors, LIG3 and PARP1, in Tyrosine Kinase-activated Leukemias

Por Muvarak, Nidal, Kelley, Shannon, Robert, Carine, Baer, Maria R., Perrotti, Danilo, Gambacorti-Passerini, Carlo, Civin, Curt, Scheibner, Kara, Rassool, Feyruz
Publicado no Mol Cancer Res (2015)

Pim kinase inhibition sensitizes FLT3-ITD acute myeloid leukemia cells to topoisomerase 2 inhibitors through increased DNA damage and oxidative stress

Por Doshi, Kshama A., Trotta, Rossana, Natarajan, Karthika, Rassool, Feyruz V., Tron, Adriana E., Huszar, Dennis, Perrotti, Danilo, Baer, Maria R.
Publicado no Oncotarget (2016)

Comment on “PP2A inhibition sensitizes cancer stem cells to ABL tyrosine kinase inhibitors in BCR-ABL human leukemia”

Por Perrotti, Danilo, Agarwal, Anupriya, Lucas, Claire M., Narla, Goutham, Neviani, Paolo, Odero, Maria D., Ruvolo, Peter P., Verrills, Nicole M.
Publicado no Sci Transl Med (2019)