Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia Pestis Outer Protein H (YopH) Phosphatase, ,

Por Bahta, Medhanit, Lountos, George T., Dyas, Beverly, Kim, Sung-Eun, Ulrich, Robert G., Waugh, David S., Burke, Terrence R.
Publicado em 2011

Structure-activity relationships and docking studies of synthetic 2-arylindole derivatives determined with aromatase and quinone reductase 1

Por Prior, Allan M., Yu, Xufen, Park, Eun-Jung, Kondratyuk, Tamara P., Lin, Yan, Pezzuto, John M., Sun, Dianqing
Publicado no Bioorg Med Chem Lett (2017)

The effects of phenolic glycosides from Betula platyphylla var. japonica on adipocyte differentiation and mature adipocyte metabolism

Por Huh, Joo Young, Lee, Seulah, Ma, Eun-Bi, Eom, Hee Jeong, Baek, Jiwon, Ko, Yoon-Joo, Kim, Ki Hyun
Publicado no J Enzyme Inhib Med Chem (2018)

Design, Synthesis, and Biological Evaluation of Indenoisoquinoline Rexinoids with Chemopreventive Potential

Por Conda-Sheridan, Martin, Park, Eun-Jung, Beck, Daniel E., Narasimha Reddy, P. V., Nguyen, Trung X., Hu, Bingjie, Chen, Lian, White, Jerry J., van Breemen, Richard B., Pezzuto, John M., Cushman, Mark
Publicado em 2013

Synthesis and structure–activity relationship studies of tyrosine-based antagonists at the human P2X(7) receptor

Por Lee, Ga Eun, Joshi, Bhalchandra V., Chen, Wangzhong, Jeong, Lak Shin, Moon, Hyung Ryong, Jacobson, Kenneth A., Kim, Yong-Chul
Publicado em 2007

Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents

Por Shen, Li, Park, Eun-Jung, Kondratyuk, Tamara P., Guendisch, Daniela, Marler, Laura, Pezzuto, John M., Wright, Anthony D., Sun, Dianqing
Publicado em 2011

Design and Synthesis of a Novel and Selective Kappa Opioid Receptor (KOR) Antagonist (BTRX-335140)

Por Guerrero, Miguel, Urbano, Mariangela, Kim, Eun-Kyong, Gamo, Ana M., Riley, Sean, Abgaryan, Lusine, Leaf, Nora, Van Orden, Lori Jean, Brown, Steven J., Xie, Jennifer Y., Porreca, Frank, Cameron, Michael D., Rosen, Hugh, Roberts, Edward
Publicado no J Med Chem (2019)

Synthesis and evaluation of quinoxaline derivatives as potential influenza NS1A protein inhibitors

Por You, Lei, Cho, Eun Jeong, Leavitt, John, Ma, Li-Chung, Montelione, Gaetano T., Anslyn, Eric V., Krug, Robert M., Ellington, Andrew, Robertus, Jon D.
Publicado em 2011

Selective Synthesis and Biological Evaluation of Sulfate-Conjugated Resveratrol Metabolites

Por Hoshino, Juma, Park, Eun-Jung, Kondratyuk, Tamara P., Marler, Laura, Pezzuto, John M., van Breemen, Richard B., Mo, Shunyan, Li, Yongchao, Cushman, Mark
Publicado em 2010

Potent and Selective Inhibitors of Human Reticulocyte 12/15-Lipoxygenase as Anti-Stroke Therapies

Por Rai, Ganesha, Joshi, Netra, Jung, Joo Eun, Liu, Yu, Schultz, Lena, Yasgar, Adam, Perry, Steve, Diaz, Giovanni, Zhang, Qiangli, Kenyon, Victor, Jadhav, Ajit, Simeonov, Anton, Lo, Eng H., van Leyen, Klaus, Maloney, David J., Holman, Theodore R.
Publicado em 2014

Structural Basis of Wee Kinases Functionality and Inactivation by Diverse Small Molecule Inhibitors

Por Zhu, Jin-Yi, Cuellar, Rebecca A., Berndt, Norbert, Lee, Hee Eun, Olesen, Sanne H., Martin, Mathew P., Jensen, Jeffrey T., Georg, Gunda I., Schönbrunn, Ernst
Publicado no J Med Chem (2017)

Synthesis, characterization and antineoplastic activity of bis-aziridinyl dimeric naphthoquinone - a novel class of compounds with potent activity against acute myeloid leukemia ce...

Por Carter-Cooper, Brandon A., Fletcher, Steven, Ferraris, Dana, Choi, Eun Yong, Kronfli, Dahlia, Dash, Smaraki, Truong, Phuc, Sausville, Edward A., Lapidus, Rena G., Emadi, Ashkan
Publicado no Bioorg Med Chem Lett (2016)

Potential Chemopreventive Agents Based on the Structure of the Lead Compound 2-Bromo-1-hydroxyphenazine, Isolated from Streptomyces sp., Strain CNS284

Por Conda-Sheridan, Martin, Marler, Laura, Park, Eun-Jung, Kondratyuk, Tamara P., Jermihov, Katherine, Mesecar, Andrew D., Pezzuto, John M., Asolkar, Ratnakar N., Fenical, William, Cushman, Mark
Publicado em 2010

Identification, Synthesis, and Biological Evaluation of the Metabolites of 3-Amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a Promising Rexinoid Lea...

Por Chen, Lian, Conda-Sheridan, Martin, Narasimha Reddy, P. V., Morrell, Andrew, Park, Eun-Jung, Kondratyuk, Tamara P., Pezzuto, John M., van Breemen, Richard B., Cushman, Mark
Publicado em 2012

Synthesis of a potent and selective (18)F-labeled δ-opioid receptor antagonist derived from the Dmt-Tic pharmacophore for PET imaging

Por Ryu, Eun Kyoung, Wu, Zhanhong, Chen, Kai, Lazarus, Lawrence H., Marczak, Ewa, D., Sasaki, Yusuke, Ambo, Akihiro, Salvadori, Severo, Ren, Chuancheng, Zhao, Heng, Balboni, Gianfranco, Chen, Xiaoyuan
Publicado em 2008

2′,6′-Dihalostyrylanilines, Pyridines, and Pyrimidines for the Inhibition of the Catalytic Subunit of Methionine S-Adenosyltransferase-2

Por Sviripa, Vitaliy M., Zhang, Wen, Balia, Andrii G., Tsodikov, Oleg V., Nickell, Justin R., Gizard, Florence, Yu, Tianxin, Lee, Eun Y., Dwoskin, Linda P., Liu, Chunming, Watt, David S.
Publicado em 2014

Synthesis and biological evaluation of pyrrolidine-based T-type calcium channel inhibitors for the treatment of neuropathic pain

Por Yang, Hak Kyun, Son, Woo Seung, Lim, Keon Seung, Kim, Gun Hee, Lim, Eun Jeong, Gadhe, Changdev G., Lee, Jae Yeol, Jeong, Kyu-Sung, Lim, Sang Min, Pae, Ae Nim
Publicado no J Enzyme Inhib Med Chem (2018)

Synthesis and Biological Evaluation of Novel Homoisoflavonoids for Retinal Neovascularization

Por Basavarajappa, Halesha D., Lee, Bit, Lee, Hyungjun, Sulaiman, Rania S., An, Hongchan, Magaña, Carlos, Shadmand, Mehdi, Vayl, Alexandra, Rajashekhar, Gangaraju, Kim, Eun-Yeong, Suh, Young-Ger, Lee, Kiho, Seo, Seung-Yong, Corson, Timothy W.
Publicado no J Med Chem (2015)

(E)-N'-Arylidene-2-(4-oxoquinazolin-4(3H)-yl) acetohydrazides: Synthesis and evaluation of antitumor cytotoxicity and caspase activation activity

Por Huan, Le Cong, Phuong, Cao Viet, Truc, Le Cong, Thanh, Vo Nguyen, Pham-The, Hai, Huong, Le-Thi-Thu, Thuan, Nguyen Thi, Park, Eun Jae, Ji, A Young, Kang, Jong Soon, Han, Sang-Bae, Tran, Phuong-Thao, Nam, Nguyen-Hai
Publicado no J Enzyme Inhib Med Chem (2019)

Synthesis and Biological Evaluation of Manassantin Analogues for Hypoxia-Inducible Factor 1α Inhibition

Por Kwon, Do-Yeon, Lee, Hye Eun, Weitzel, Douglas H., Park, Kyunghye, Lee, Sun Hee, Lee, Chen-Ting, Stephenson, Tesia N., Park, Hyeri, Fitzgerald, Michael C., Chi, Jen-Tsan, Mook, Robert A., Dewhirst, Mark W., Lee, You Mie, Hong, Jiyong
Publicado no J Med Chem (2015)