Viral destruction of cell surface receptors

Por Mesecar, Andrew D., Ratia, Kiira
Publicado em 2008

A 2.2 Å resolution structure of the USP7 catalytic domain in a new space group elaborates upon structural rearrangements resulting from ubiquitin binding

Por Molland, Katrina, Zhou, Qing, Mesecar, Andrew D.
Publicado em 2014

Cul3-mediated Nrf2 ubiquitination and ARE activation are dependent on the partial molar volume at position 151 of Keap1

Por Eggler, Aimee L., Small, Evan, Hannink, Mark, Mesecar, Andrew D.
Publicado em 2009

X-Ray Structure and Inhibition of 3C-like Protease from Porcine Epidemic Diarrhea Virus

Por St. John, Sarah E., Anson, Brandon J., Mesecar, Andrew D.
Publicado no Sci Rep (2016)

Structural and mechanistic analysis of trans-3-chloroacrylic acid dehalogenase activity

Por Pegan, Scott D., Serrano, Hector, Whitman, Christian P., Mesecar, Andrew D.
Publicado em 2008

Structural basis for catalysis of a tetrameric, class IIa fructose 1,6-bisphosphate aldolase from M. tuberculosis

Por Pegan, Scott D., Rukseree, Kamolchanok, Franzblau, Scott G., Mesecar, Andrew D.
Publicado em 2009

Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2

Por CALAMINI, Barbara, SANTARSIERO, Bernard D., BOUTIN, Jean A., MESECAR, Andrew D.
Publicado em 2008

Nidovirus papain-like proteases: Multifunctional enzymes with protease, deubiquitinating and deISGylating activities

Por Mielech, Anna M., Chen, Yafang, Mesecar, Andrew D., Baker, Susan C.
Publicado em 2014

Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF-κB Signaling

Por Frieman, Matthew, Ratia, Kiira, Johnston, Robert E., Mesecar, Andrew D., Baric, Ralph S.
Publicado em 2009

Bacillus anthracis o-succinylbenzoyl-CoA synthetase: reaction kinetics and a novel inhibitor mimicking its reaction intermediate

Por Tian, Yang, Suk, Dae-Hwan, Cai, Feng, Crich, David, Mesecar, Andrew D.
Publicado em 2008

Modification of Keap1 Cysteine Residues by Sulforaphane

Por Hu, Chenqi, Eggler, Aimee L., Mesecar, Andrew D., van Breemen, Richard B.
Publicado em 2011

Evaluating the 3C-like protease activity of SARS-Coronavirus: Recommendations for standardized assays for drug discovery

Por Grum-Tokars, Valerie, Ratia, Kiira, Begaye, Adrian, Baker, Susan C., Mesecar, Andrew D.
Publicado em 2008

The Papain-Like Protease of Severe Acute Respiratory Syndrome Coronavirus Has Deubiquitinating Activity

Por Barretto, Naina, Jukneliene, Dalia, Ratia, Kiira, Chen, Zhongbin, Mesecar, Andrew D., Baker, Susan C.
Publicado em 2005

Progress in Anti-SARS Coronavirus Chemistry, Biology and Chemotherapy

Por Ghosh, Arun K., Xi, Kai, Johnson, Michael E., Baker, Susan C., Mesecar, Andrew D.
Publicado em 2006

Screening for Natural Chemoprevention Agents that Modify Human Keap1

Por Hu, Chenqi, Nikolic, Dejan, Eggler, Aimee L., Mesecar, Andrew D., van Breemen, Richard B.
Publicado em 2011

Catalytic Function and Substrate Specificity of the Papain-Like Protease Domain of nsp3 from the Middle East Respiratory Syndrome Coronavirus

Por Báez-Santos, Yahira M., Mielech, Anna M., Deng, Xufang, Baker, Susan, Mesecar, Andrew D.
Publicado no J Virol (2014)

Modifying specific cysteines of the electrophile-sensing human Keap1 protein is insufficient to disrupt binding to the Nrf2 domain Neh2

Por Eggler, Aimee L., Liu, Guowen, Pezzuto, John M., van Breemen, Richard B., Mesecar, Andrew D.
Publicado em 2005

Proteolytic Processing and Deubiquitinating Activity of Papain-Like Proteases of Human Coronavirus NL63

Por Chen, Zhongbin, Wang, Yanhua, Ratia, Kiira, Mesecar, Andrew D., Wilkinson, Keith D., Baker, Susan C.
Publicado em 2007

Kinetic and Structural Characterization of a Heterohexamer 4-Oxalocrotonate Tautomerase from Chloroflexus aurantiacus J-10-fl: Implications for Functional and Structural Diversity...

Por Burks, Elizabeth A., Fleming, Chris D., Mesecar, Andrew D., Whitman, Christian P., Pegan, Scott D.
Publicado em 2010

X-ray structural studies of quinone reductase 2 nanomolar range inhibitors

Por Pegan, Scott D, Sturdy, Megan, Ferry, Gilles, Delagrange, Philippe, Boutin, Jean A, Mesecar, Andrew D
Publicado em 2011