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Modification of Keap1 Cysteine Residues by Sulforaphane
Activation of the transcription factor NF-E2-related factor-2 (Nrf2) through modification of Kelch-like ECH-associated protein 1 (Keap1) cysteines, leading to up-regulation of the antioxidant response element (ARE), is an important mechanism of cellular defense against reactive oxygen species and xe...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3086360/ https://ncbi.nlm.nih.gov/pubmed/21391649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx100389r |
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