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Sites of Alkylation of Human Keap1 by Natural Chemoprevention Agents
Under basal conditions, the interaction of the cytosolic protein Keap1 with the transcription factor Nrf2 results in a low level of expression of cytoprotective genes whose promoter region contains the antioxidant response element (ARE). Alkylation of one or more of the 27 cysteine sulfhydryl groups...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2144741/ https://ncbi.nlm.nih.gov/pubmed/17980616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jasms.2007.09.015 |
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