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Biotransformation of the chemopreventive agent isoliquiritigenin by UDP-glucuronosyltransferases

Isoliquiritigenin (2’,4’,4-trihydroxychalcone), a chalcone found in licorice root and shallots, exhibits antioxidant, estrogenic, and anti-tumor activities. To complement our previous studies concerning the phase 1 metabolism of isoliquiritigenin, the phase 2 transformation of isoliquiritigenin by h...

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Detalhes bibliográficos
Main Authors: Guo, Jian, Liu, Ang, Cao, Hongmei, Luo, Yan, Pezzuto, John M., van Breemen, Richard B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615638/
https://ncbi.nlm.nih.gov/pubmed/18653743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.108.021857
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