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Nidovirus papain-like proteases: Multifunctional enzymes with protease, deubiquitinating and deISGylating activities

Coronaviruses and arteriviruses, members of the order Nidovirales, are positive strand RNA viruses that encode large replicase polyproteins that are processed by viral proteases to generate the nonstructural proteins which mediate viral RNA synthesis. The viral papain-like proteases (PLPs) are criti...

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Detalhes bibliográficos
Main Authors: Mielech, Anna M., Chen, Yafang, Mesecar, Andrew D., Baker, Susan C.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4125544/
https://ncbi.nlm.nih.gov/pubmed/24512893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2014.01.025
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