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Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease

Coronavirus papain-like proteases (PLPs or PLpro), such as the one encoded in the genome of the infectious Middle East Respiratory Syndrome (MERS) virus, have multiple enzymatic activities that promote viral infection. PLpro acts as a protease and processes the large coronavirus polyprotein for viru...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Clasman, Jozlyn R., Everett, Renata K., Srinivasan, Karthik, Mesecar, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: Published by Elsevier B.V. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7114298/
https://ncbi.nlm.nih.gov/pubmed/31765674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2019.104661
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