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Structural Basis for the Ubiquitin-Linkage Specificity and deISGylating Activity of SARS-CoV Papain-Like Protease

Severe acute respiratory syndrome coronavirus (SARS-CoV) encodes a papain-like protease (PLpro) with both deubiquitinating (DUB) and deISGylating activities that are proposed to counteract the post-translational modification of signaling molecules that activate the innate immune response. Here we ex...

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Bibliografische gegevens
Hoofdauteurs: Ratia, Kiira, Kilianski, Andrew, Baez-Santos, Yahira M., Baker, Susan C., Mesecar, Andrew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031219/
https://ncbi.nlm.nih.gov/pubmed/24854014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004113
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