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MERS-CoV papain-like protease has deISGylating and deubiquitinating activities
Coronaviruses encode papain-like proteases (PLpro) that are often multifunctional enzymes with protease activity to process the viral replicase polyprotein and deubiquitinating (DUB)/deISGylating activity, which is hypothesized to modify the innate immune response to infection. Here, we investigate...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Elsevier Inc.
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3957432/ https://ncbi.nlm.nih.gov/pubmed/24503068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.11.040 |
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