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Severe Acute Respiratory Syndrome Coronavirus Papain-Like Protease Ubiquitin-Like Domain and Catalytic Domain Regulate Antagonism of IRF3 and NF-κB Signaling

The outcome of a viral infection is regulated in part by the complex coordination of viral and host interactions that compete for the control and optimization of virus replication. Severe acute respiratory syndrome coronavirus (SARS-CoV) intimately engages and regulates the host innate immune respon...

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Detalhes bibliográficos
Main Authors: Frieman, Matthew, Ratia, Kiira, Johnston, Robert E., Mesecar, Andrew D., Baric, Ralph S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2698564/
https://ncbi.nlm.nih.gov/pubmed/19369340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02220-08
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