Synthesis and Tautomerization of Hydroxylated Isoflavones Bearing Heterocyclic Hemi-Aminals

Por Frasinyuk, Mykhaylo S., Bondarenko, Svitlana P., Khilya, Volodymyr P., Liu, Chunming, Watt, David S., Sviripa, Vitaliy M.
Publicado no Org Biomol Chem (2014)

Tritium-labeled (E,E)-2,5-Bis(4’-hydroxy-3’-carboxystyryl)benzene as a Probe for β-Amyloid Fibrils

Por Matveev, Sergey V., Kwiatkowski, Stefan, Sviripa, Vitaliy M., Fazio, Robert C., Watt, David S., LeVine, Harry
Publicado no Bioorg Med Chem Lett (2014)

Synthesis of a Norcantharidin-tethered Guanosine: Protein Phosphatase-1 Inhibitors That Change Alternative Splicing

Por Kwiatkowski, Stefan, Sviripa, Vitaliy M., Zhang, Zhaiyi, Wendlandt, Alison E., Höbartner, Claudia, Watt, David S., Stamm, Stefan
Publicado no Bioorg Med Chem Lett (2015)

Development of 6H-Chromeno[3,4-c]pyrido[3',2':4,5]thieno[2,3-e]pyridazin-6-ones as Par-4 Secretagogues

Por Frasinyuk, Mykhaylo S., Bondarenko, Svitlana P., Sviripa, Vitaliy M., Burikhanov, Ravshan, Rangnekar, Vivek M., Liu, Chunming, Watt, David S.
Publicado no Tetrahedron Lett (2015)

Induction of AMPK activation by N,N’-diarylurea FND-4b decreases growth and increases apoptosis in triple negative and estrogen-receptor positive breast cancers

Por Johnson, Jeremy, Rychahou, Piotr, Sviripa, Vitaliy M., Weiss, Heidi L., Liu, Chunming, Watt, David S., Evers, B. Mark
Publicado no PLoS One (2019)

Fluorinated N,N′-Diarylureas As Novel Therapeutic Agents Against Cancer Stem Cells

Por Kenlan, Dasha E., Rychahou, Piotr, Sviripa, Vitaliy M., Weiss, Heidi L., Liu, Chunming, Watt, David S., Evers, B. Mark
Publicado no Mol Cancer Ther (2017)

Halogenated Diarylacetylenes Repress c-Myc Expression in Cancer Cells

Por Sviripa, Vitaliy M., Zhang, Wen, Kril, Liliia M., Liu, Alice X., Yuan, Yaxia, Zhan, Chang-Guo, Liu, Chunming, Watt, David S.
Publicado em 2014

Quantification of trans-2,6-difluoro-4′-N,N-dimethylaminostilbene in rat plasma: Application to a pharmacokinetic study

Por Lin, Hai-Shu, Sviripa, Vitaliy M., Watt, David S., Liu, Chunming, Xiang, Tian-Xiang, Anderson, Bradley D., Ong, Pei Shi, Ho, Paul C.
Publicado em 2012

Arylquins Target Vimentin to Trigger Par-4 Secretion for Tumor Cell Apoptosis

Por Burikhanov, Ravshan, Sviripa, Vitaliy M., Hebbar, Nikhil, Zhang, Wen, Layton, W. John, Hamza, Adel, Zhan, Chang-Guo, Watt, David S., Liu, Chunming, Rangnekar, Vivek M.
Publicado em 2014

N-Aryl Benzenesulfonamide Inhibitors of [(3)H]-Thymidine Incorporation and β-Catenin Signaling in Human Hepatocyte-derived Huh-7 Carcinoma Cells

Por Kril, Liliia M., Vilchez, Valery, Jiang, Jieyun, Turcios, Lilia, Chen, Changguo, Sviripa, Vitaliy M., Zhang, Wen, Liu, Chunming, Spear, Brett, Watt, David S., Gedaly, Roberto
Publicado no Bioorg Med Chem Lett (2015)

Application of Mannich Bases to the Synthesis of Hydroxymethylated Isoflavonoids As Potential Antineoplastic Agents

Por Frasinyuk, Mykhaylo S., Mrug, Galyna P., Bondarenko, Svitlana P., Sviripa, Vitaliy M., Zhang, Wen, Cai, Xianfeng, Fiandalo, Michael V., Mohler, James L., Liu, Chunming, Watt, David S.
Publicado no Org Biomol Chem (2015)

Bis(N-amidinohydrazones) and N-(amidino)-N'-aryl-bishydrazones: New classes of antibacterial/antifungal agents

Por Shrestha, Sanjib K., Kril, Liliia M., Green, Keith D., Kwiatkowski, Stefan, Sviripa, Vitaliy M., Nickell, Justin R., Dwoskin, Linda P., Watt, David S., Garneau-Tsodikova, Sylvie
Publicado no Bioorg Med Chem (2016)

Phenylethynyl-substituted heterocycles inhibit cyclin D1 and induce the expression of cyclin-dependent kinase inhibitor p21(Wif1/Cip1) in colorectal cancer cells

Por Sviripa, Vitaliy M., Kril, Liliia M., Zhang, Wen, Xie, Yanqi, Wyrebek, Przemyslaw, Ponomareva, Larissa, Liu, Xifu, Yuan, Yaxia, Zhan, Chang-Guo, Watt, David S., Liu, Chunming
Publicado no Medchemcomm (2017)

2′,6′-Dihalostyrylanilines, Pyridines, and Pyrimidines for the Inhibition of the Catalytic Subunit of Methionine S-Adenosyltransferase-2

Por Sviripa, Vitaliy M., Zhang, Wen, Balia, Andrii G., Tsodikov, Oleg V., Nickell, Justin R., Gizard, Florence, Yu, Tianxin, Lee, Eun Y., Dwoskin, Linda P., Liu, Chunming, Watt, David S.
Publicado em 2014

Synthesis and Characterization of Pseudocantharidins, Novel Phosphatase Modulators That Promote the Inclusion of Exon 7 into the SMN (Survival of Motoneuron) pre-mRNA

Por Zhang, Zhaiyi, Kelemen, Olga, van Santen, Maria A., Yelton, Sharon M., Wendlandt, Alison E., Sviripa, Vitaliy M., Bollen, Mathieu, Beullens, Monique, Urlaub, Henning, Lührmann, Reinhard, Watt, David S., Stamm, Stefan
Publicado em 2011

Par-4 Secretion: Stoichiometry of 3-Arylquinoline Binding to Vimentin

Por Sviripa, Vitaliy M., Burikhanov, Ravshan, Obiero, Josiah M., Yuan, Yaxia, Nickell, Justin R., Dwoskin, Linda P., Zhan, Chang-Guo, Liu, Chunming, Tsodikov, Oleg V., Rangnekar, Vivek M., Watt, David S.
Publicado no Org Biomol Chem (2016)

Antineoplastic Isoflavonoids Derived from Intermediate ortho-Quinone Methides Generated from Mannich Bases

Por Frasinyuk, Mykhaylo S., Mrug, Galyna P., Bondarenko, Svitlana P., Khilya, Volodymyr P., Sviripa, Vitaliy M., Syrotchuk, Oleksandr A., Zhang, Wen, Cai, Xianfeng, Fiandalo, Michael V., Mohler, James L., Liu, Chunming, Watt, David S.
Publicado no ChemMedChem (2016)

Developing Antineoplastic Agents that Targeting Peroxisomal Enzymes: Cytisine-linked Isoflavonoids as Inhibitors of Hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)

Por Frasinyuk, Mykhaylo S., Zhang, Wen, Wyrebek, Przemyslaw, Yu, Tianxin, Xu, Xuehe, Sviripa, Vitaliy M., Bondarenko, Svitlana P., Xie, Yanqi, Ngo, Huy X., Morris, Andrew J., Mohler, James L., Fiandalo, Michael V., Watt, David S., Liu, Chunming
Publicado no Org Biomol Chem (2017)

Semisynthetic aurones inhibit tubulin polymerization at the colchicine-binding site and repress PC-3 tumor xenografts in nude mice and myc-induced T-ALL in zebrafish

Por Xie, Yanqi, Kril, Liliia M., Yu, Tianxin, Zhang, Wen, Frasinyuk, Mykhaylo S., Bondarenko, Svitlana P., Kondratyuk, Kostyantyn M., Hausman, Elizabeth, Martin, Zachary M., Wyrebek, Przemyslaw P., Liu, Xifu, Deaciuc, Agripina, Dwoskin, Linda P., Chen, Jing, Zhu, Haining, Zhan, Chang-Guo, Sviripa, Vitaliy M., Blackburn, Jessica, Watt, David S., Liu, Chunming
Publicado no Sci Rep (2019)