Current approaches for the discovery of drugs that deter substance and drug abuse

著者: Yasgar, Adam, Simeonov, Anton
出版年 Expert Opin Drug Discov (2014)

AlphaScreen-Based Assays: Ultra-High-Throughput Screening for Small-Molecule Inhibitors of Challenging Enzymes and Protein-Protein Interactions

著者: Yasgar, Adam, Jadhav, Ajit, Simeonov, Anton, Coussens, Nathan P.
出版年 Methods Mol Biol (2016)

A Strategy to Discover Inhibitors of Bacillus subtilis Surfactin-type Phosphopantetheinyl Transferase

著者: Yasgar, Adam, Foley, Timothy, Jadhav, Ajit, Inglese, James, Burkart, Michael, Simeonov, Anton
出版事項 2009

High-Throughput 1,536-Well Fluorescence Polarization Assays for α(1)-Acid Glycoprotein and Human Serum Albumin Binding

著者: Yasgar, Adam, Furdas, Silviya D., Maloney, David J., Jadhav, Ajit, Jung, Manfred, Simeonov, Anton
出版事項 2012

Preparation of FRET Reporters to Support Chemical Probe Development

著者: Foley, Timothy L., Yasgar, Adam, Garcia, Christopher J., Jadhav, Ajit, Simeonov, Anton, Burkart, Michael D.
出版事項 2010

Fluorescence polarization assays in high-throughput screening and drug discovery: a review

著者: Hall, Matthew D, Yasgar, Adam, Peryea, Tyler, Braisted, John C, Jadhav, Ajit, Simeonov, Anton, Coussens, Nathan P
出版年 Methods Appl Fluoresc (2016)

Quantitative high-throughput screening: A titration-based approach that efficiently identifies biological activities in large chemical libraries

著者: Inglese, James, Auld, Douglas S., Jadhav, Ajit, Johnson, Ronald L., Simeonov, Anton, Yasgar, Adam, Zheng, Wei, Austin, Christopher P.
出版事項 2006

The NCGC Pharmaceutical Collection: A comprehensive resource of clinically approved drugs enabling repurposing and chemical genomics

著者: Huang, Ruili, Southall, Noel, Wang, Yuhong, Yasgar, Adam, Shinn, Paul, Jadhav, Ajit, Nguyen, Dac-Trung, Austin, Christopher P.
出版事項 2011

Compound Management for Quantitative High-Throughput Screening

著者: Yasgar, Adam, Shinn, Paul, Jadhav, Ajit, Auld, Douglas, Michael, Sam, Zheng, Wei, Austin, Christopher P., Inglese, James, Simeonov, Anton
出版事項 2008

Dual-Fluorophore Quantitative High-throughput Screen for Inhibitors of BRCT-Phosphoprotein Interaction

著者: Simeonov, Anton, Yasgar, Adam, Jadhav, Ajit, Lokesh, G. L., Klumpp, Carleen, Michael, Sam, Austin, Christopher P., Natarajan, Amarnath, Inglese, James
出版事項 2007

Optimization of High-Throughput Methyltransferase Assays for the Discovery of Small Molecule Inhibitors

著者: Dong, Guangping, Yasgar, Adam, Peterson, Darrell L., Zakharov, Alexey, Talley, Daniel, Cheng, Ken Chih-Chien, Jadhav, Ajit, Simeonov, Anton, Huang, Rong
出版年 ACS Comb Sci (2020)

A High-Throughput 1,536-Well Luminescence Assay for Glutathione S-Transferase Activity

著者: Yasgar, Adam, Shultz, John, Zhou, Wenhui, Wang, Hui, Huang, Fen, Murphy, Nancy, Abel, Erika L., DiGiovanni, John, Inglese, James, Simeonov, Anton
出版事項 2010

High throughput identification of promiscuous inhibitors from screening libraries with the use of a thiol-containing fluorescent probe

著者: McCallum, Megan M., Nandhikonda, Premchendar, Temmer, Jonathan J., Eyermann, Charles, Simeonov, Anton, Jadhav, Ajit, Yasgar, Adam, Maloney, David, Arnold, Leggy A.
出版事項 2013

A fluorescence-based high throughput assay for the determination of small molecule–human serum albumin protein binding

著者: McCallum, Megan M., Pawlak, Alan J., Shadrick, William R., Simeonov, Anton, Jadhav, Ajit, Yasgar, Adam, Maloney, David J., Arnold, Leggy A.
出版事項 2014

Selective small molecule inhibitor of the Mycobacterium tuberculosis fumarate hydratase reveals an allosteric regulatory site

著者: Kasbekar, Monica, Fischer, Gerhard, Mott, Bryan T., Yasgar, Adam, Hyvönen, Marko, Boshoff, Helena I. M., Abell, Chris, Barry, Clifton E., Thomas, Craig J.
出版年 Proc Natl Acad Sci U S A (2016)

A parallel chemistry approach to identify novel nuclear receptor ligands based on the GW0742 scaffold

著者: Teske, Kelly A., Rai, Ganesha, Nandhikonda, Premchendar, Sidhu, Preetpal S., Feleke, Belaynesh, Simeonov, Anton, Yasgar, Adam, Jadhav, Ajit, Maloney, David J., Arnold, Leggy A.
出版年 ACS Comb Sci (2017)

Structure-Activity Relationship Studies and Biological Characterization of Human NAD(+)-dependent 15-Hydroxyprostaglandin Dehydrogenase Inhibitors

著者: Duveau, Damien Y., Yasgar, Adam, Wang, Yuhong, Hu, Xin, Kouznetsova, Jennifer, Brimacombe, Kyle R., Jadhav, Ajit, Simeonov, Anton, Thomas, Craig J., Maloney, David J.
出版事項 2013

A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

著者: Yasgar, Adam, Titus, Steven A., Wang, Yuhong, Danchik, Carina, Yang, Shyh-Ming, Vasiliou, Vasilis, Jadhav, Ajit, Maloney, David J., Simeonov, Anton, Martinez, Natalia J.
出版年 PLoS One (2017)

Correction: A High-Content Assay Enables the Automated Screening and Identification of Small Molecules with Specific ALDH1A1-Inhibitory Activity

著者: Yasgar, Adam, Titus, Steven A., Wang, Yuhong, Danchik, Carina, Yang, Shyh-Ming, Vasiliou, Vasilis, Jadhav, Ajit, Maloney, David J., Simeonov, Anton, Martinez, Natalia J.
出版年 PLoS One (2018)

A High-Throughput Fluorescence Polarization Assay for Inhibitors of the GoLoco Motif/G-alpha Interaction

著者: Kimple, Adam J., Yasgar, Adam, Hughes, Mark, Jadhav, Ajit, Willard, Francis S., Muller, Robin E., Austin, Christopher P., Inglese, James, Ibeanu, Gordon C., Siderovski, David P., Simeonov, Anton
出版事項 2008