Kinetics of DNA Unwinding by the RecD2 Helicase from Deinococcus radiodurans

Yazar: Shadrick, William R., Julin, Douglas A.
Baskı/Yayın Bilgisi 2010

Identification and Analysis of Inhibitors Targeting the Hepatitis C Virus NS3 Helicase

Yazar: Hanson, Alicia M., Hernandez, John J., Shadrick, William R., Frick, David N.
Baskı/Yayın Bilgisi 2012

Aurintricarboxylic acid modulates the affinity of hepatitis C virus NS3 helicase for both nucleic acid and ATP()

Yazar: Shadrick, William R., Mukherjee, Sourav, Hanson, Alicia M., Sweeney, Noreena L., Frick, David N.
Yayımlandı Biochemistry (2013)

Discovering New Medicines Targeting Helicases: Challenges and Recent Progress

Yazar: Shadrick, William R., Ndjomou, Jean, Kolli, Rajesh, Mukherjee, Sourav, Hanson, Alicia M., Frick, David N.
Yayımlandı SLAS Discov (2013)

Primuline Derivatives That Mimic RNA to Stimulate Hepatitis C Virus NS3 Helicase-catalyzed ATP Hydrolysis

Yazar: Sweeney, Noreena L., Shadrick, William R., Mukherjee, Sourav, Li, Kelin, Frankowski, Kevin J., Schoenen, Frank J., Frick, David N.
Baskı/Yayın Bilgisi 2013

A fluorescence-based high throughput assay for the determination of small molecule–human serum albumin protein binding

Yazar: McCallum, Megan M., Pawlak, Alan J., Shadrick, William R., Simeonov, Anton, Jadhav, Ajit, Yasgar, Adam, Maloney, David J., Arnold, Leggy A.
Baskı/Yayın Bilgisi 2014

Pterin-sulfa conjugates as dihydropteroate synthase inhibitors and antibacterial agents

Yazar: Zhao, Ying, Shadrick, William R., Wallace, Miranda J., Wu, Yinan, Griffith, Elizabeth C., Qi, Jianjun, Yun, Mi-Kyung, White, Stephen W., Lee, Richard E.
Yayımlandı Bioorg Med Chem Lett (2016)

Fluorescent Primuline Derivatives Inhibit Hepatitis C Virus NS3-Catalyzed RNA Unwinding, Peptide Hydrolysis and Viral Replicase Formation

Yazar: Ndjomou, Jean, Kolli, Rajesh, Mukherjee, Sourav, Shadrick, William R., Hanson, Alicia M., Sweeney, Noreena L., Bartczak, Diana, Li, Kelin, Frankowski, Kevin J., Schoenen, Frank J., Frick, David N.
Baskı/Yayın Bilgisi 2012

Structures of trehalose-6-phosphate phosphatase from pathogenic fungi reveal the mechanisms of substrate recognition and catalysis

Yazar: Miao, Yi, Tenor, Jennifer L., Toffaletti, Dena L., Washington, Erica J., Liu, Jiuyu, Shadrick, William R., Schumacher, Maria A., Lee, Richard E., Perfect, John R., Brennan, Richard G.
Yayımlandı Proc Natl Acad Sci U S A (2016)

Identification and characterization of influenza variants resistant to a viral endonuclease inhibitor

Yazar: Song, Min-Suk, Kumar, Gyanendra, Shadrick, William R., Zhou, Wei, Jeevan, Trushar, Li, Zhenmei, Slavish, P. Jake, Fabrizio, Thomas P., Yoon, Sun-Woo, Webb, Thomas R., Webby, Richard J., White, Stephen W.
Yayımlandı Proc Natl Acad Sci U S A (2016)

Identification and analysis of hepatitis C virus NS3 helicase inhibitors using nucleic acid binding assays

Yazar: Mukherjee, Sourav, Hanson, Alicia M., Shadrick, William R., Ndjomou, Jean, Sweeney, Noreena L., Hernandez, John J., Bartczak, Diana, Li, Kelin, Frankowski, Kevin J., Heck, Julie A., Arnold, Leggy A., Schoenen, Frank J., Frick, David N.
Baskı/Yayın Bilgisi 2012

Exploiting a water network to achieve enthalpy-driven, bromodomain-selective BET inhibitors

Yazar: Shadrick, William R., Slavish, Peter J., Chai, Sergio C., Waddell, Brett, Connelly, Michele, Low, Jonathan A., Tallant, Cynthia, Young, Brandon M., Bharatham, Nagakumar, Knapp, Stefan, Boyd, Vincent A., Morfouace, Marie, Roussel, Martine F., Chen, Taosheng, Lee, Richard E., Guy, R. Kiplin, Shelat, Anang A., Potter, Philip M.
Yayımlandı Bioorg Med Chem (2017)

Ureadepsipeptides as ClpP Activators

Yazar: Griffith, Elizabeth C., Zhao, Ying, Singh, Aman P., Conlon, Brian P., Tangallapally, Rajendra, Shadrick, William R., Liu, Jiuyu, Wallace, Miranda J., Yang, Lei, Elmore, John M., Li, Yong, Zheng, Zhong, Miller, Darcie J., Cheramie, Martin N., Lee, Robin B., LaFleur, Michael D., Lewis, Kim, Lee, Richard E.
Yayımlandı ACS Infect Dis (2019)

Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer

Yazar: Slavish, P. Jake, Chi, Liying, Yun, Mi-Kyung, Tsurkan, Lyudmila, Martinez, Nancy E., Jonchere, Barbara, Chai, Sergio C., Connelly, Michele, Waddell, M. Brett, Das, Sourav, Neale, Geoffrey, Li, Zhenmei, Shadrick, William R., Olsen, Rachelle R., Freeman, Kevin W., Low, Jonathan A., Price, Jeanine E., Young, Brandon M., Bharatham, Nagakumar, Boyd, Vincent A., Yang, Jun, Lee, Richard E., Morfouace, Marie, Roussel, Martine F., Chen, Taosheng, Savic, Daniel, Guy, R. Kiplin, White, Stephen W., Shelat, Anang A., Potter, Philip M.
Yayımlandı Cancer Res (2020)