Transcriptional enhancers in development and disease

por Sakabe, Noboru Jo, Savic, Daniel, Nobrega, Marcelo A
Publicado 2012

An in vivo cis-Regulatory Screen at the Type 2 Diabetes Associated TCF7L2 Locus Identifies Multiple Tissue-Specific Enhancers

por Savic, Daniel, Bell, Graeme I., Nobrega, Marcelo A.
Publicado 2012

Mapping genome-wide transcription factor binding sites in frozen tissues

por Savic, Daniel, Gertz, Jason, Jain, Preti, Cooper, Gregory M, Myers, Richard M
Publicado 2013

Decoding transcriptional enhancers: Evolving from annotation to functional interpretation

por Engel, Krysta L., Mackiewicz, Mark, Hardigan, Andrew A., Myers, Richard M., Savic, Daniel
Publicado en Semin Cell Dev Biol (2016)

Alterations in TCF7L2 expression define its role as a key regulator of glucose metabolism

por Savic, Daniel, Ye, Honggang, Aneas, Ivy, Park, Soo-Young, Bell, Graeme I., Nobrega, Marcelo A.
Publicado 2011

Modulation of Tcf7l2 Expression Alters Behavior in Mice

por Savic, Daniel, Distler, Margaret G., Sokoloff, Greta, Shanahan, Nancy A., Dulawa, Stephanie C., Palmer, Abraham A., Nobrega, Marcelo A.
Publicado 2011

A genome-wide interactome of DNA-associated proteins in the human liver

por Ramaker, Ryne C., Savic, Daniel, Hardigan, Andrew A., Newberry, Kimberly, Cooper, Gregory M., Myers, Richard M., Cooper, Sara J.
Publicado en Genome Res (2017)

CCCTC-Binding Factor Translates Interleukin 2- and α-Ketoglutarate-Sensitive Metabolic Changes in T Cells into Context-Dependent Gene Programs

por Chisolm, Danielle A., Savic, Daniel, Moore, Amanda J., Ballesteros-Tato, Andre, León, Beatriz, Crossman, David K., Murre, Cornelis, Myers, Richard M., Weinmann, Amy S.
Publicado en Immunity (2017)

CETCh-seq: CRISPR epitope tagging ChIP-seq of DNA-binding proteins

por Savic, Daniel, Partridge, E. Christopher, Newberry, Kimberly M., Smith, Sophia B., Meadows, Sarah K., Roberts, Brian S., Mackiewicz, Mark, Mendenhall, Eric M., Myers, Richard M.
Publicado en Genome Res (2015)

Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

por Savic, Daniel, Roberts, Brian S., Carleton, Julia B., Partridge, E. Christopher, White, Michael A., Cohen, Barak A., Cooper, Gregory M., Gertz, Jason, Myers, Richard M.
Publicado en Genome Res (2015)

Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in mice

por Bailey, Kathleen A., Savic, Daniel, Zielinski, Mark, Park, Soo-Young, Wang, Ling-jia, Witkowski, Piotr, Brady, Matthew, Hara, Manami, Bell, Graeme I., Nobrega, Marcelo A.
Publicado en Hum Mol Genet (2015)

Batf Pioneers the Reorganization of Chromatin in Developing Effector T Cells via Ets1-Dependent Recruitment of Ctcf

por Pham, Duy, Moseley, Carson E., Gao, Min, Savic, Daniel, Winstead, Colleen J., Sun, Mengxi, Kee, Barbara L., Myers, Richard M., Weaver, Casey T., Hatton, Robin D.
Publicado en Cell Rep (2019)

Distinct properties of cell type-specific and shared transcription factor binding sites

por Gertz, Jason, Savic, Daniel, Varley, Katherine E., Partridge, E. Christopher, Safi, Alexias, Jain, Preti, Cooper, Gregory M., Reddy, Timothy E., Crawford, Gregory E., Myers, Richard M.
Publicado 2013

Distinct gene regulatory programs define the inhibitory effects of liver X receptors and PPARG on cancer cell proliferation

por Savic, Daniel, Ramaker, Ryne C., Roberts, Brian S., Dean, Emma C., Burwell, Todd C., Meadows, Sarah K., Cooper, Sara J., Garabedian, Michael J., Gertz, Jason, Myers, Richard M.
Publicado en Genome Med (2016)

Occupancy maps of 208 chromatin-associated proteins in one human cell type

por Partridge, E. Christopher, Chhetri, Surya B., Prokop, Jeremy W., Ramaker, Ryne C., Jansen, Camden S., Goh, Say-Tar, Mackiewicz, Mark, Newberry, Kimberly M., Brandsmeier, Laurel A., Meadows, Sarah K., Messer, C. Luke, Hardigan, Andrew A., Coppola, Candice J., Dean, Emma C., Jiang, Shan, Savic, Daniel, Mortazavi, Ali, Wold, Barbara J., Myers, Richard M., Mendenhall, Eric M.
Publicado en Nature (2020)

Genomic regulation of invasion by STAT3 in triple negative breast cancer

por McDaniel, Joy M., Varley, Katherine E., Gertz, Jason, Savic, Daniel S., Roberts, Brian S., Bailey, Sarah K., Shevde, Lalita A., Ramaker, Ryne C., Lasseigne, Brittany N., Kirby, Marie K., Newberry, Kimberly M., Christopher Partridge, E ., Jones, Angela L., Boone, Braden, Levy, Shawn E., Oliver, Patsy G., Sexton, Katherine C., Grizzle, William E., Forero, Andres, Buchsbaum, Donald J., Cooper, Sara J., Myers, Richard M.
Publicado en Oncotarget (2016)

Bromodomain-selective BET inhibitors are potent antitumor agents against MYC-driven pediatric cancer

por Slavish, P. Jake, Chi, Liying, Yun, Mi-Kyung, Tsurkan, Lyudmila, Martinez, Nancy E., Jonchere, Barbara, Chai, Sergio C., Connelly, Michele, Waddell, M. Brett, Das, Sourav, Neale, Geoffrey, Li, Zhenmei, Shadrick, William R., Olsen, Rachelle R., Freeman, Kevin W., Low, Jonathan A., Price, Jeanine E., Young, Brandon M., Bharatham, Nagakumar, Boyd, Vincent A., Yang, Jun, Lee, Richard E., Morfouace, Marie, Roussel, Martine F., Chen, Taosheng, Savic, Daniel, Guy, R. Kiplin, White, Stephen W., Shelat, Anang A., Potter, Philip M.
Publicado en Cancer Res (2020)

Integrative genomic analyses reveal mechanisms of glucocorticoid resistance in acute lymphoblastic leukemia

por Autry, Robert J., Paugh, Steven W., Carter, Robert, Shi, Lei, Liu, Jingjing, Ferguson, Daniel C., Lau, Calvin E., Bonten, Erik J., Yang, Wenjian, McCorkle, J. Robert, Beard, Jordan A., Panetta, John C., Diedrich, Jonathan D., Crews, Kristine R., Pei, Deqing, Coke, Christopher J., Natarajan, Sivaraman, Khatamian, Alireza, Karol, Seth E., Lopez-Lopez, Elixabet, Diouf, Barthelemy, Smith, Colton, Gocho, Yoshihiro, Hagiwara, Kohei, Roberts, Kathryn G., Pounds, Stanley, Kornblau, Steven M., Stock, Wendy, Paietta, Elisabeth M., Litzow, Mark R., Inaba, Hiroto, Mullighan, Charles G., Jeha, Sima, Pui, Ching-Hon, Cheng, Cheng, Savic, Daniel, Yu, Jiyang, Gawad, Charles, Relling, Mary V., Yang, Jun J., Evans, William E.
Publicado en Nat Cancer (2020)

NALP3 inflammasome up-regulation and CASP1 cleavage of the glucocorticoid receptor causes glucocorticoid resistance in leukemia cells

por Paugh, Steven W., Bonten, Erik J., Savic, Daniel, Ramsey, Laura B., Thierfelder, William E., Gurung, Prajwal, Malireddi, R. K. Subbarao, Actis, Marcelo, Mayasundari, Anand, Min, Jaeki, Coss, David R., Laudermilk, Lucas T., Panetta, John C., McCorkle, J. Robert, Fan, Yiping, Crews, Kristine R., Stocco, Gabriele, Wilkinson, Mark R., Ferreira, Antonio M., Cheng, Cheng, Yang, Wenjian, Karol, Seth E., Fernandez, Christian A., Diouf, Barthelemy, Smith, Colton, Hicks, J. Kevin, Zanut, Alessandra, Giordanengo, Audrey, Crona, Daniel, Bianchi, Joy J., Holmfeldt, Linda, Mullighan, Charles G., den Boer, Monique L., Pieters, Rob, Jeha, Sima, Dunwell, Thomas L., Latif, Farida, Bhojwani, Deepa, Carroll, William L., Pui, Ching-Hon, Myers, Richard M., Guy, R. Kiplin, Kanneganti, Thirumala-Devi, Relling, Mary V., Evans, William E.
Publicado en Nat Genet (2015)