Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

Transcription factors (TFs) bind to thousands of DNA sequences in mammalian genomes, but most of these binding events appear to have no direct effect on gene expression. It is unclear why only a subset of TF bound sites are actively involved in transcriptional regulation. Moreover, the key genomic f...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Savic, Daniel, Roberts, Brian S., Carleton, Julia B., Partridge, E. Christopher, White, Michael A., Cohen, Barak A., Cooper, Gregory M., Gertz, Jason, Myers, Richard M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665001/
https://ncbi.nlm.nih.gov/pubmed/26486725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.191593.115
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