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Promoter-distal RNA polymerase II binding discriminates active from inactive CCAAT/ enhancer-binding protein beta binding sites

Transcription factors (TFs) bind to thousands of DNA sequences in mammalian genomes, but most of these binding events appear to have no direct effect on gene expression. It is unclear why only a subset of TF bound sites are actively involved in transcriptional regulation. Moreover, the key genomic f...

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Dettagli Bibliografici
Pubblicato in:Genome Res
Autori principali: Savic, Daniel, Roberts, Brian S., Carleton, Julia B., Partridge, E. Christopher, White, Michael A., Cohen, Barak A., Cooper, Gregory M., Gertz, Jason, Myers, Richard M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665001/
https://ncbi.nlm.nih.gov/pubmed/26486725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.191593.115
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