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Loop II of DNA Polymerase Beta is Important for Discrimination During Substrate Binding

Loop II of DNA polymerase beta (pol β) consists of fourteen amino acid residues and is highly flexible and solvent exposed. Previous research from our laboratory has shown that this loop is important for polymerase activity and fidelity. In the study presented here, we demonstrate that a shortened f...

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Detalhes bibliográficos
Main Authors: Lin, George C., Jaeger, Joachim, Eckert, Kristin A., Sweasy, Joann B
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2653711/
https://ncbi.nlm.nih.gov/pubmed/19013261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2008.10.006
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