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A Triad Interaction in the Fingers Subdomain of DNA Polymerase Beta Controls Polymerase Activity

[Image: see text] DNA polymerase beta (pol beta) is the main polymerase involved in the base excision repair pathway responsible for repairing damaged bases in the DNA. Previous studies on the H285D mutant of pol beta suggested that the C-terminal region of the polymerase is important for polymerase...

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Main Authors: Murphy, Drew L., Jaeger, Joachim, Sweasy, Joann B.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3601662/
https://ncbi.nlm.nih.gov/pubmed/21452873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja111099b
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