The Leu22Pro tumor-associated variant of DNA polymerase beta is dRP lyase deficient

Lignende værker

• Requirements for 5′dRP/AP lyase activity in Ku
  af: Strande, Natasha T., et al.
  Udgivet: (2014)
• Loop II of DNA polymerase beta is important for polymerization activity and fidelity
  af: Lin, George C., et al.
  Udgivet: (2007)
• Human DNA polymerase θ possesses 5′-dRP lyase activity and functions in single-nucleotide base excision repair in vitro
  af: Prasad, Rajendra, et al.
  Udgivet: (2009)
• Gastric cancer associated variant of DNA polymerase beta (Leu22Pro) promotes DNA replication associated double strand breaks
  af: Rozacky, Jenna, et al.
  Udgivet: (2015)
• The E295K DNA Polymerase Beta Gastric Cancer-Associated Variant Interferes with Base Excision Repair and Induces Cellular Transformation
  af: Lang, Tieming, et al.
  Udgivet: (2007)