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Requirements for 5′dRP/AP lyase activity in Ku
The non-homologous end joining (NHEJ) pathway is used in diverse species to repair chromosome breaks, and is defined in part by a requirement for Ku. We previously demonstrated mammalian Ku has intrinsic 5′ deoxyribosephosphate (5′dRP) and apurinic/apyrimidinic (AP) lyase activity, and showed this a...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Oxford University Press
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4176175/ https://ncbi.nlm.nih.gov/pubmed/25200085 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku796 |
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