Identification of a conserved 5′-dRP lyase activity in bacterial DNA repair ligase D and its potential role in base excision repair

Bacillus subtilis is one of the bacterial members provided with a nonhomologous end joining (NHEJ) system constituted by the DNA-binding Ku homodimer that recruits the ATP-dependent DNA Ligase D (BsuLigD) to the double-stranded DNA breaks (DSBs) ends. BsuLigD has inherent polymerization and ligase a...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: de Ory, Ana, Nagler, Katja, Carrasco, Begoña, Raguse, Marina, Zafra, Olga, Moeller, Ralf, de Vega, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4770248/
https://ncbi.nlm.nih.gov/pubmed/26826709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw054
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