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DNA polymerase β is the major dRP lyase involved in repair of oxidative base lesions in DNA by mammalian cell extracts

The repair of oxidative base lesions in DNA is a coordinated chain of reactions that includes removal of the damaged base, incision of the phosphodiester backbone at the abasic sugar residue, incorporation of an undamaged nucleotide and sealing of the DNA strand break. Although removal of a damaged...

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Autors principals: Allinson, Sarah L., Dianova, Irina I., Dianov, Grigory L.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC125762/
https://ncbi.nlm.nih.gov/pubmed/11726527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.23.6919
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