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The E288K Colon Tumor Variant of DNA Polymerase β Is a Sequence Specific Mutator
[Image: see text] DNA polymerase β (pol β) is the main polymerase involved in base excision repair (BER), which is a pathway responsible for the repair of tens of thousands of DNA lesions per cell per day. Our recent efforts in sequencing colon tumors showed that 40% of the tumors sequenced possesse...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3667668/ https://ncbi.nlm.nih.gov/pubmed/22650412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi3003583 |
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