Genomic approaches for understanding the genetics of complex disease

par Lowe, William L., Reddy, Timothy E.
Publié dans Genome Res (2015)

Binding Site Graphs: A New Graph Theoretical Framework for Prediction of Transcription Factor Binding Sites

par Reddy, Timothy E, DeLisi, Charles, Shakhnovich, Boris E
Publié 2007

Functional Genomics of Healthy and Pathological Fetal Membranes

par Cunningham, Sarah J., Feng, Liping, Allen, Terrence K., Reddy, Timothy E.
Publié dans Front Physiol (2020)

Positional clustering improves computational binding site detection and identifies novel cis-regulatory sites in mammalian GABA(A) receptor subunit genes

par Reddy, Timothy E., Shakhnovich, Boris E., Roberts, Daniel S., Russek, Shelley J., DeLisi, Charles
Publié 2007

Genistein and bisphenol A exposure cause estrogen receptor 1 to bind thousands of sites in a cell type-specific manner

par Gertz, Jason, Reddy, Timothy E., Varley, Katherine E., Garabedian, Michael J., Myers, Richard M.
Publié 2012

The Hypersensitive Glucocorticoid Response Specifically Regulates Period 1 and Expression of Circadian Genes

par Reddy, Timothy E., Gertz, Jason, Crawford, Gregory E., Garabedian, Michael J., Myers, Richard M.
Publié 2012

A long-range flexible billboard model of gene activation

par Vockley, Christopher M., McDowell, Ian C., D'Ippolito, Antony M., Reddy, Timothy E.
Publié dans Transcription (2017)

Predicting gene structure changes resulting from genetic variants via exon definition features

par Majoros, William H, Holt, Carson, Campbell, Michael S, Ware, Doreen, Yandell, Mark, Reddy, Timothy E
Publié dans Bioinformatics (2018)

New Insights Into Gestational Glucose Metabolism: Lessons Learned From 21st Century Approaches

par Angueira, Anthony R., Ludvik, Anton E., Reddy, Timothy E., Wicksteed, Barton, Lowe, William L., Layden, Brian T.
Publié dans Diabetes (2015)

Allele-specific distribution of RNA polymerase II on female X chromosomes

par Kucera, Katerina S., Reddy, Timothy E., Pauli, Florencia, Gertz, Jason, Logan, Jenae E., Myers, Richard M., Willard, Huntington F.
Publié 2011

Multiplex CRISPR/Cas9-Based Genome Editing for Correction of Dystrophin Mutations that Cause Duchenne Muscular Dystrophy

par Ousterout, David G., Kabadi, Ami M., Thakore, Pratiksha I., Majoros, William H., Reddy, Timothy E., Gersbach, Charles A.
Publié dans Nat Commun (2015)

Clustering gene expression time series data using an infinite Gaussian process mixture model

par McDowell, Ian C., Manandhar, Dinesh, Vockley, Christopher M., Schmid, Amy K., Reddy, Timothy E., Engelhardt, Barbara E.
Publié dans PLoS Comput Biol (2018)

Transversions have larger regulatory effects than transitions

par Guo, Cong, McDowell, Ian C., Nodzenski, Michael, Scholtens, Denise M., Allen, Andrew S., Lowe, William L., Reddy, Timothy E.
Publié dans BMC Genomics (2017)

AP-1 subunits converge promiscuously at enhancers to potentiate transcription

par Seo, Jungkyun, Koçak, D. Dewran, Bartelt, Luke C., Williams, Courtney A., Barrera, Alejandro, Gersbach, Charles A., Reddy, Timothy E.
Publié dans Genome Res (2021)

Genomic determination of the glucocorticoid response reveals unexpected mechanisms of gene regulation

par Reddy, Timothy E., Pauli, Florencia, Sprouse, Rebekka O., Neff, Norma F., Newberry, Kimberly M., Garabedian, Michael J., Myers, Richard M.
Publié 2009

High-throughput interpretation of gene structure changes in human and nonhuman resequencing data, using ACE

par Majoros, William H, Campbell, Michael S, Holt, Carson, DeNardo, Erin K, Ware, Doreen, Allen, Andrew S, Yandell, Mark, Reddy, Timothy E
Publié dans Bioinformatics (2017)

Genome-wide quantification of the effects of DNA methylation on human gene regulation

par Lea, Amanda J, Vockley, Christopher M, Johnston, Rachel A, Del Carpio, Christina A, Barreiro, Luis B, Reddy, Timothy E, Tung, Jenny
Publié dans eLife (2018)

Evidence for multiple roles for grainyhead-like 2 in the establishment and maintenance of human mucociliary airway epithelium

par Gao, Xia, Vockley, Christopher M., Pauli, Florencia, Newberry, Kimberly M., Xue, Yan, Randell, Scott H., Reddy, Timothy E., Hogan, Brigid L. M.
Publié 2013

Epigenome editing by a CRISPR/Cas9-based acetyltransferase activates genes from promoters and enhancers

par Hilton, Isaac B., D’Ippolito, Anthony M., Vockley, Christopher M., Thakore, Pratiksha I., Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Publié dans Nat Biotechnol (2015)

Massively parallel quantification of the regulatory effects of noncoding genetic variation in a human cohort

par Vockley, Christopher M., Guo, Cong, Majoros, William H., Nodzenski, Michael, Scholtens, Denise M., Hayes, M. Geoffrey, Lowe, William L., Reddy, Timothy E.
Publié dans Genome Res (2015)