The Development of TALE Nucleases for Biotechnology

by Ousterout, David G., Gersbach, Charles A.
Published in Methods Mol Biol (2016)

Feline Lectin Activity Is Critical for the Cellular Entry of Feline Infectious Peritonitis Virus

by Regan, Andrew D., Ousterout, David G., Whittaker, Gary R.
Published 2010

Advances in Targeted Genome Editing

by Perez-Pinera, Pablo, Ousterout, David G., Gersbach, Charles A.
Published 2012

Gene targeting to the ROSA26 locus directed by engineered zinc finger nucleases

by Perez-Pinera, Pablo, Ousterout, David G., Brown, Matthew T., Gersbach, Charles A.
Published 2012

Multiplex CRISPR/Cas9-based genome engineering from a single lentiviral vector

by Kabadi, Ami M., Ousterout, David G., Hilton, Isaac B., Gersbach, Charles A.
Published in Nucleic Acids Res (2014)

Multiplex CRISPR/Cas9-Based Genome Editing for Correction of Dystrophin Mutations that Cause Duchenne Muscular Dystrophy

by Ousterout, David G., Kabadi, Ami M., Thakore, Pratiksha I., Majoros, William H., Reddy, Timothy E., Gersbach, Charles A.
Published in Nat Commun (2015)

Correction of Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients Through Genomic Excision of Exon 51 by Zinc Finger Nucleases

by Ousterout, David G, Kabadi, Ami M, Thakore, Pratiksha I, Perez-Pinera, Pablo, Brown, Matthew T, Majoros, William H, Reddy, Timothy E, Gersbach, Charles A
Published in Mol Ther (2015)

Enhanced MyoD-Induced Transdifferentiation to a Myogenic Lineage by Fusion to a Potent Transactivation Domain

by Kabadi, Ami M., Thakore, Pratiksha I., Vockley, Christopher M., Ousterout, David G., Gibson, Tyler M., Guilak, Farshid, Reddy, Timothy E., Gersbach, Charles A.
Published in ACS Synth Biol (2014)

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

by Perez-Pinera, Pablo, Ousterout, David G., Brunger, Jonathan M., Farin, Alicia M., Glass, Katherine A., Guilak, Farshid, Crawford, Gregory E., Hartemink, Alexander J., Gersbach, Charles A.
Published 2013

Reading Frame Correction by Targeted Genome Editing Restores Dystrophin Expression in Cells From Duchenne Muscular Dystrophy Patients

by Ousterout, David G, Perez-Pinera, Pablo, Thakore, Pratiksha I, Kabadi, Ami M, Brown, Matthew T, Qin, Xiaoxia, Fedrigo, Olivier, Mouly, Vincent, Tremblay, Jacques P, Gersbach, Charles A
Published 2013

In Vivo Targeting of Clostridioides difficile Using Phage-Delivered CRISPR-Cas3 Antimicrobials

by Selle, Kurt, Fletcher, Joshua R., Tuson, Hannah, Schmitt, Daniel S., McMillan, Lana, Vridhambal, Gowrinarayani S., Rivera, Alissa J., Montgomery, Stephanie A., Fortier, Louis-Charles, Barrangou, Rodolphe, Theriot, Casey M., Ousterout, David G.
Published in mBio (2020)

Highly active zinc-finger nucleases by extended modular assembly

by Bhakta, Mital S., Henry, Isabelle M., Ousterout, David G., Das, Kumitaa Theva, Lockwood, Sarah H., Meckler, Joshua F., Wallen, Mark C., Zykovich, Artem, Yu, Yawei, Leo, Heather, Xu, Lifeng, Gersbach, Charles A., Segal, David J.
Published 2013

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

by Nelson, Christopher E., Hakim, Chady H., Ousterout, David G., Thakore, Pratiksha I., Moreb, Eirik A., Rivera, Ruth M. Castellanos, Madhavan, Sarina, Pan, Xiufang, Ran, F. Ann, Yan, Winston X., Asokan, Aravind, Zhang, Feng, Duan, Dongsheng, Gersbach, Charles A.
Published in Science (2015)

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

by Perez-Pinera, Pablo, Kocak, D. Dewran, Vockley, Christopher M., Adler, Andrew F., Kabadi, Ami M., Polstein, Lauren R., Thakore, Pratiksha I., Glass, Katherine A., Ousterout, David G., Leong, Kam W., Guilak, Farshid, Crawford, Gregory E., Reddy, Timothy E., Gersbach, Charles A.
Published 2013